Cardiology Division, Medicine Department, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925. Vila Clementino, São Paulo, SP 04024-002, Brazil.
Sleep Breath. 2013 May;17(2):837-43. doi: 10.1007/s11325-012-0774-3. Epub 2012 Oct 26.
Obstructive sleep apnea (OSA) is a risk factor for cardiovascular disease. Strong associations have been reported among sleep duration, hypertension, obesity, and cardiovascular mortality. The authors hypothesize that sleep duration may play a role in OSA severity. The aim of this study is to analyze sleep duration in OSA patients.
Patients who underwent overnight polysomnography were consecutively selected from the Sleep Clinic of Universidade Federal de São Paulo database between March 2009 and December 2010. All subjects were asked to come to the Sleep Clinic at 8:00 a.m. for a clinical evaluation and actigraphy. Anthropometric parameters such as weight, height, hip circumference, abdominal circumference, and neck circumference were also measured.
One hundred thirty-three patients were divided into four groups based on total sleep time, sleep efficiency, sleep latency, and wake after sleep onset: very short sleepers (n = 11), short sleepers (n = 21), intermediate sleepers (n = 56), and sufficient sleepers (n = 45). Apnea-hypopnea index (AHI) was higher in very short sleepers (50.18 ± 30.86 events/h) compared with intermediate sleepers (20.36 ± 14.68 events/h; p = 0.007) and sufficient sleepers (23.21 ± 20.45 events/h; p = 0.02). Minimal and mean arterial oxygen saturation and time spent below 90 % oxygen saturation exhibited worse values in very short sleepers. After adjustment for gender, age, AHI, and body mass index, mean oxygen saturation was significantly associated to total sleep time (p = 0.01).
In conclusion, the present study suggests that sleep duration may be associated to low mean oxygen saturation in OSA patients.
阻塞性睡眠呼吸暂停（OSA）是心血管疾病的一个危险因素。已有研究报道，睡眠持续时间、高血压、肥胖症和心血管死亡率之间存在很强的相关性。作者假设睡眠持续时间可能在 OSA 严重程度中发挥作用。本研究旨在分析 OSA 患者的睡眠持续时间。
从 2009 年 3 月至 2010 年 12 月期间，连续从圣保罗联邦大学睡眠诊所的过夜多导睡眠图数据库中选择接受检查的患者。所有患者均被要求在上午 8 点到睡眠诊所进行临床评估和活动记录仪检查。还测量了体重、身高、臀围、腰围和颈围等人体测量参数。
根据总睡眠时间、睡眠效率、睡眠潜伏期和睡眠后觉醒时间，将 133 名患者分为四组：极短睡眠时间组（n=11）、短睡眠时间组（n=21）、中等睡眠时间组（n=56）和充足睡眠时间组（n=45）。极短睡眠时间组的呼吸暂停低通气指数（AHI）更高（50.18±30.86 次/小时），与中等睡眠时间组（20.36±14.68 次/小时；p=0.007）和充足睡眠时间组（23.21±20.45 次/小时；p=0.02）相比。极短睡眠时间组的最小和平均动脉血氧饱和度以及血氧饱和度低于 90%的时间均较差。在校正性别、年龄、AHI 和体重指数后，平均血氧饱和度与总睡眠时间显著相关（p=0.01）。
总之，本研究表明，睡眠持续时间可能与 OSA 患者的平均血氧饱和度较低有关。
