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根治性前列腺切除术后阴茎长度的自然史:一项长期前瞻性研究。

The natural history of penile length after radical prostatectomy: a long-term prospective study.

机构信息

Service of Urology, Pedro Ernesto Memorial Hospital, Rio de Janeiro State University, Rio de Janeiro, Rio de Janeiro, Brazil.

出版信息

Urology. 2012 Dec;80(6):1293-6. doi: 10.1016/j.urology.2012.07.060. Epub 2012 Oct 23.

DOI:10.1016/j.urology.2012.07.060
PMID:23102441
Abstract

OBJECTIVE

To describe the penile length after radical prostatectomy (RP) in a long-term follow-up.

MATERIALS AND METHODS

We evaluated prospectively the penile length of 105 patients with localized prostate cancer treated by open RP. Participants using therapy for penile rehabilitation were excluded from statistical analysis. Measurements of the stretched penis were taken preoperatively and at 3, 6, 12, 24, 36, 48, and 60 months postoperatively. The International Index of Erectile Function-Erectile Function (IIEF-EF) questionnaire was used to evaluate erectile function. The penile anthropometric measure used was the stretched length of the flaccid penis, from the pubopenile skin angle to the end of the glans, after the prepubic fat was depressed under maximum manual traction.

RESULTS

The mean stretched penile length 3 months after RP decreased an average of 1 cm from baseline (P <.001). This mean difference persisted until 24 months. At 36 months, the penile length differed 0.6 cm. At 48 months (-0.3 cm) and 60 months (+0.4 cm), the mean differences in penile length before and after RP were not significant (P = .080 and P = .065, respectively). Erectile function was a predictor for early return of penile length.

CONCLUSION

Nearly 1 cm of penile shortening after RP may be expected up to 12 months. However, a trend toward recovery of penile length occurs after 24 months of follow-up and is completely re-established after 48 months. The preserved erectile function after RP is a predictor for penile length recovery.

摘要

目的

描述根治性前列腺切除术后(RP)的阴茎长度的长期随访结果。

材料和方法

我们前瞻性评估了 105 例局限性前列腺癌患者接受开放式 RP 治疗后的阴茎长度。排除接受阴茎康复治疗的患者进行统计学分析。术前和术后 3、6、12、24、36、48 和 60 个月时测量伸展阴茎的长度。使用国际勃起功能指数-勃起功能(IIEF-EF)问卷评估勃起功能。使用的阴茎人体测量指标是疲软阴茎的伸展长度,即耻骨前脂肪在最大手动牵引下被压下后,从耻骨-阴茎皮肤角度到龟头末端的距离。

结果

RP 术后 3 个月,伸展阴茎的平均长度比基线平均减少 1 厘米(P<0.001)。这种平均差异一直持续到 24 个月。36 个月时,阴茎长度相差 0.6 厘米。48 个月(-0.3 厘米)和 60 个月(+0.4 厘米)时,RP 前后阴茎长度的平均差异无统计学意义(P=0.080 和 P=0.065)。勃起功能是阴茎长度早期恢复的预测因素。

结论

RP 后可能会出现近 1 厘米的阴茎缩短,这一情况可持续至 12 个月。然而,在 24 个月的随访后,会出现阴茎长度恢复的趋势,并且在 48 个月后完全恢复。RP 后保留的勃起功能是阴茎长度恢复的预测因素。

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