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世界卫生组织关于甲型肝炎疫苗的立场文件:2012 年 6 月——建议。

WHO position paper on hepatitis A vaccines: June 2012-recommendations.

出版信息

Vaccine. 2013 Jan 2;31(2):285-6. doi: 10.1016/j.vaccine.2012.10.102. Epub 2012 Nov 8.

DOI:10.1016/j.vaccine.2012.10.102
PMID:23142134
Abstract

This article presents the World Health Organizations (WHO) recommendations onthe use of hepatitis A vaccine excerpted from the WHO position paper on hepatitis A vaccines - June 2012 recently published in the Weekly Epidemiological Record [1]. The current document replaces the position paper on the use of hepatitis A vaccines published in 2000 [2] and incorporates the most recent developments in the field with particular consideration to changes in the epidemiological features of hepatitis A infection in several countries, increased supply of hepatitis A vaccines, and new evidence on their public health benefits. Footnotes to this paper provide a number of core references including references to grading tables that assess the quality of scientific evidence for a few key conclusions. In accordance with its mandate to provide guidance to Member States on health policy matters, WHO issues a series of regularly updated position papers on vaccines and combinations of vaccines against diseases that have an international public health impact. These papers are concerned primarily with the use of vaccines in large-scale immunization programmes; they summarize essential background information on diseases and vaccines, and conclude with WHO's current position on the use of vaccines in the global context. This paper reflects the recommendations of WHO's Strategic Advisory Group of Experts (SAGE) on immunization. These recommendations were discussed by SAGE at its November 2011 and April 2012 meetings. Evidence presented at these meetings can be accessed at http://www.who.int/immunization/sage/previous/en/index.html.

摘要

本文摘录了世界卫生组织(世卫组织)关于甲型肝炎疫苗使用的建议,该建议出自最近发表在《每周流行病学记录》[1]上的世卫组织甲型肝炎疫苗立场文件(2012 年 6 月)。本文件取代了 2000 年发表的关于甲型肝炎疫苗使用的立场文件[2],并纳入了该领域的最新进展,特别考虑到几个国家甲型肝炎感染的流行病学特征变化、甲型肝炎疫苗供应增加以及公共卫生效益的新证据。本文脚注提供了一些核心参考文献,包括对评估少数关键结论的科学证据质量的分级表的参考文献。根据其在世卫组织成员国的卫生政策事项上提供指导的任务,世卫组织定期发布关于具有国际公共卫生影响的疾病的疫苗和疫苗组合的立场文件。这些文件主要涉及大规模免疫规划中疫苗的使用;它们总结了有关疾病和疫苗的必要背景信息,并以世卫组织在全球背景下对疫苗使用的当前立场结束。本文反映了世卫组织免疫战略咨询专家组(SAGE)的建议。这些建议在 SAGE 2011 年 11 月和 2012 年 4 月的会议上进行了讨论。这些会议上提出的证据可在以下网址查阅:http://www.who.int/immunization/sage/previous/en/index.html。

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