Department of Ophthalmology, International University of Health and Welfare, Mita Hospital, Tokyo, Japan.
Rejuvenation Res. 2013 Feb;16(1):35-42. doi: 10.1089/rej.2012.1369.
Gait speed and sleep quality are health indices related to longevity and mortality. In the present study, we measured sleep quality, quality of life, gait speed, and visual acuity before and after cataract surgery to evaluate the efficacy of the procedure on systemic health.
The study was conducted on 155 patients (93 women; average age 74.8 years) undergoing cataract surgery with the implantation of a yellow soft acrylic lens. Patients were evaluated using the Pittsburgh Sleep Quality Index (PSQI) and the National Eye Institute Visual Function Questionnaire 25 (VFQ-25; vision-related quality of life) before and then 2 and 7 months after surgery. Four-meter gait speed was also determined.
Of the 155 patients, 68 (43.9%) were classified as poor sleepers (PSQI>5.5) prior to surgery. Significant improvements were noted in sleep 2 months after surgery (p<0.05, paired t-test), but thereafter the improvements were not significant. Prior to surgery, 117 patients (77.0%) were classified as slow walkers (speed<1.0 meter/s). Gait speed increased significantly in these patients 2 months after surgery (p<0.001, paired t-test). Multiple regression analysis revealed significant correlations between the preoperative VFQ-25 score and both PSQI (p<0.05) and gait speed (p<0.001). Postoperative increases in the VFQ-25 score were positively correlated with decreases in the PSQI (p<0.05). Improvements in visual acuity were correlated with improvements in the VFQ-25 score, but not with either PSQI or gait speed.
Cataract surgery effectively improves sleep quality and slow gait speed.
步态速度和睡眠质量是与长寿和死亡率相关的健康指标。在本研究中,我们测量了白内障手术后的睡眠质量、生活质量、步态速度和视力,以评估该手术对全身健康的疗效。
该研究纳入了 155 名接受白内障手术(植入黄色软性丙烯酸晶状体)的患者(93 名女性;平均年龄 74.8 岁)。使用匹兹堡睡眠质量指数(PSQI)和国家眼科研究所视觉功能问卷 25 项(VFQ-25;与视力相关的生活质量)在术前、术后 2 个月和 7 个月对患者进行评估。还测定了 4 米步态速度。
在 155 名患者中,有 68 名(43.9%)患者在术前被归类为睡眠质量差(PSQI>5.5)。术后 2 个月睡眠质量有显著改善(p<0.05,配对 t 检验),但此后改善不显著。术前,有 117 名患者(77.0%)被归类为步态缓慢(速度<1.0 米/秒)。这些患者术后 2 个月的步态速度显著提高(p<0.001,配对 t 检验)。多元回归分析显示,术前 VFQ-25 评分与 PSQI(p<0.05)和步态速度(p<0.001)均显著相关。术后 VFQ-25 评分的增加与 PSQI 的降低呈正相关(p<0.05)。视力的改善与 VFQ-25 评分的改善相关,与 PSQI 或步态速度无关。
白内障手术可有效改善睡眠质量和步态缓慢。