Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, P.R. China.
Nat Prod Res. 2013 Aug;27(15):1353-60. doi: 10.1080/14786419.2012.740034. Epub 2012 Nov 16.
Two new triterpenoid saponins celosin I (1) and celosin II (2) were isolated from the seeds of Celosia argentea L. (Amaranthaceae). The structures of the two new compounds were elucidated based on chemical analysis and spectral methods (IR, 1-D and 2-D NMR, ESI-MS, HR-ESI-MS). They exhibited significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice.
从青葙（苋科）种子中分离得到两种新的三萜皂苷 celosin I（1）和 celosin II（2）。根据化学分析和光谱方法（IR、1-D 和 2-D NMR、ESI-MS、HR-ESI-MS）确定了这两种新化合物的结构。它们对四氯化碳和 N，N-二甲基甲酰胺诱导的小鼠肝毒性具有显著的保肝作用。
