University "Federico II" of Naples, Via Pansini 5, 80131, Naples, Italy,
Hernia. 2013 Dec;17(6):749-55. doi: 10.1007/s10029-012-1022-2. Epub 2012 Nov 16.
The aim of this prospective randomized study was to determine the utility of transversus abdominis plane (TAP) block to improve the efficacy of conventional local anaesthesia for hernia repair in order to achieve an adequate anaesthesia and to evaluate its post-operative analgesic effectiveness.
Hundred and fifty consecutive male patients undergoing outpatient hernia repair (Lichtenstein technique) were enrolled in this study. Patients were randomly allocated to undergo a combined TAP block and local anaesthesia (case group) or single conventional local anaesthesia (control group). The study was designed to obtain a 1:2 case-control ratio. The primary outcome was the evaluation of the proportion of patients achieving an adequate anaesthesia. The secondary outcome was the evaluation of pain on movement, pain at rest, rescue analgesia need, nausea and satisfaction.
An adequate anaesthesia was achieved in 8 % case and in 36 % control subjects (p = 0.001). At the 6 and 12 h post-operative evaluations, patients enrolled in the case group reported significantly less pain (evaluated by VAS score) both at rest and on movement (p always = 0.001). Moreover, the need of rescue analgesia resulted significantly higher in the control group (14 vs. 32 %, p = 0.01).
Our results demonstrated that, as compared with conventional local anaesthesia, the combination of TAP block with local anaesthesia showed a higher efficacy in the obtainment of an adequate anaesthesia and in the post-operative pain control for hernia repair.
本前瞻性随机研究旨在确定腹横肌平面(TAP)阻滞在提高传统局部麻醉疝修补术疗效中的作用,以达到充分的麻醉效果,并评估其术后镇痛效果。
本研究纳入了 150 例接受门诊疝修补术(Lichtenstein 技术)的男性患者。患者被随机分配接受 TAP 阻滞联合局部麻醉(病例组)或单纯常规局部麻醉(对照组)。该研究旨在获得 1:2 的病例对照比。主要结局是评估达到充分麻醉的患者比例。次要结局是评估运动时疼痛、休息时疼痛、需要解救镇痛、恶心和满意度。
病例组 8%的患者达到充分麻醉,对照组 36%的患者达到充分麻醉(p=0.001)。在术后 6 和 12 小时评估时,病例组患者在休息和运动时报告的疼痛(通过 VAS 评分评估)明显较轻(p 始终=0.001)。此外,对照组需要解救镇痛的患者明显较多(14%比 32%,p=0.01)。
与传统局部麻醉相比,TAP 阻滞联合局部麻醉在获得充分麻醉和术后镇痛方面显示出更高的疗效。