Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina, Facultat de Biociències Universitat Autònoma de Barcelona, Cerdanyola del Vallès 08193 Spain.
Database (Oxford). 2012 Nov 22;2012:bas035. doi: 10.1093/database/bas035. Print 2012.
The eTUMOUR (eT) multi-centre project gathered in vivo and ex vivo magnetic resonance (MR) data, as well as transcriptomic and clinical information from brain tumour patients, with the purpose of improving the diagnostic and prognostic evaluation of future patients. In order to carry this out, among other work, a database--the eTDB--was developed. In addition to complex permission rules and software and management quality control (QC), it was necessary to develop anonymization, processing and data visualization tools for the data uploaded. It was also necessary to develop sophisticated curation strategies that involved on one hand, dedicated fields for QC-generated meta-data and specialized queries and global permissions for senior curators and on the other, to establish a set of metrics to quantify its contents. The indispensable dataset (ID), completeness and pairedness indices were set. The database contains 1317 cases created as a result of the eT project and 304 from a previous project, INTERPRET. The number of cases fulfilling the ID was 656. Completeness and pairedness were heterogeneous, depending on the data type involved.
eTUMOUR（eT）多中心项目收集了脑肿瘤患者的体内和体外磁共振（MR）数据以及转录组学和临床信息，旨在改善未来患者的诊断和预后评估。为此，除了其他工作外，还开发了一个数据库--eTDB。除了复杂的权限规则和软件以及管理质量控制（QC）外，还需要为上传的数据开发匿名化、处理和数据可视化工具。还需要开发复杂的策展策略，一方面涉及为 QC 生成的元数据和专门查询以及高级策展人设置专用字段，另一方面为量化其内容设置一组指标。设置了不可或缺的数据集（ID）、完整性和配对指数。该数据库包含 1317 个由 eT 项目创建的病例和 304 个来自之前的 INTERPRET 项目的病例。符合 ID 的病例数为 656 个。完整性和配对性因涉及的数据类型而异而存在差异。
