• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

动物 QTLdb:在后基因组时代用于家畜动物 QTL/关联数据传播的改良数据库工具。

Animal QTLdb: an improved database tool for livestock animal QTL/association data dissemination in the post-genome era.

机构信息

Department of Animal Science and Center for Integrated Animal Genomics, Iowa State University, 2255 Kildee Hall, Ames, IA 50011, USA.

出版信息

Nucleic Acids Res. 2013 Jan;41(Database issue):D871-9. doi: 10.1093/nar/gks1150. Epub 2012 Nov 24.

DOI:10.1093/nar/gks1150
PMID:23180796
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3531174/
Abstract

The Animal QTL database (QTLdb; http://www.animalgenome.org/QTLdb) is designed to house all publicly available QTL and single-nucleotide polymorphism/gene association data on livestock animal species. An earlier version was published in the Nucleic Acids Research Database issue in 2007. Since then, we have continued our efforts to develop new and improved database tools to allow more data types, parameters and functions. Our efforts have transformed the Animal QTLdb into a tool that actively serves the research community as a quality data repository and more importantly, a provider of easily accessible tools and functions to disseminate QTL and gene association information. The QTLdb has been heavily used by the livestock genomics community since its first public release in 2004. To date, there are 5920 cattle, 3442 chicken, 7451 pigs, 753 sheep and 88 rainbow trout data points in the database, and at least 290 publications that cite use of the database. The rapid advancement in genomic studies of cattle, chicken, pigs, sheep and other livestock animals has presented us with challenges, as well as opportunities for the QTLdb to meet the evolving needs of the research community. Here, we report our progress over the recent years and highlight new functions and services available to the general public.

摘要

动物 QTL 数据库(QTLdb;http://www.animalgenome.org/QTLdb)旨在存储所有可公开获得的家畜物种的 QTL 和单核苷酸多态性/基因关联数据。其早期版本于 2007 年在核酸研究数据库专刊上发布。自那时起,我们一直致力于开发新的和改进的数据库工具,以允许更多的数据类型、参数和功能。我们的努力使动物 QTLdb 转变为一个工具,它不仅作为一个高质量数据存储库,而且更重要的是作为一个提供易于访问的工具和功能的提供者,来传播 QTL 和基因关联信息,积极服务于研究界。自 2004 年首次公开发布以来,家畜基因组学社区一直在大量使用该数据库。迄今为止,该数据库中已有 5920 个牛、3442 个鸡、7451 个猪、753 个羊和 88 个虹鳟鱼数据点,至少有 290 篇出版物引用了该数据库。牛、鸡、猪、羊和其他家畜的基因组研究的快速发展给 QTLdb 带来了挑战,同时也为其满足研究界不断变化的需求提供了机会。在这里,我们报告了近年来的进展,并强调了向公众提供的新功能和服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/561562277d6e/gks1150f5p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/98836d9d564e/gks1150f1p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/bd8a5a3c90a7/gks1150f2p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/431b7f13b6e1/gks1150f3p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/4da1422763fa/gks1150f4p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/561562277d6e/gks1150f5p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/98836d9d564e/gks1150f1p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/bd8a5a3c90a7/gks1150f2p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/431b7f13b6e1/gks1150f3p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/4da1422763fa/gks1150f4p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afcc/3531174/561562277d6e/gks1150f5p.jpg

相似文献

1
Animal QTLdb: an improved database tool for livestock animal QTL/association data dissemination in the post-genome era.动物 QTLdb:在后基因组时代用于家畜动物 QTL/关联数据传播的改良数据库工具。
Nucleic Acids Res. 2013 Jan;41(Database issue):D871-9. doi: 10.1093/nar/gks1150. Epub 2012 Nov 24.
2
Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services.将动物 QTLdb 和 CorrDB 带入未来:迎接新挑战,提供更新的服务。
Nucleic Acids Res. 2022 Jan 7;50(D1):D956-D961. doi: 10.1093/nar/gkab1116.
3
Animal QTLdb: beyond a repository. A public platform for QTL comparisons and integration with diverse types of structural genomic information.动物数量性状基因座数据库:超越一个储存库。一个用于数量性状基因座比较以及与多种类型结构基因组信息整合的公共平台。
Mamm Genome. 2007 Jan;18(1):1-4. doi: 10.1007/s00335-006-0105-8. Epub 2007 Jan 23.
4
AnimalQTLdb: a livestock QTL database tool set for positional QTL information mining and beyond.动物数量性状基因座数据库:一个用于定位数量性状基因座信息挖掘及其他用途的家畜数量性状基因座数据库工具集。
Nucleic Acids Res. 2007 Jan;35(Database issue):D604-9. doi: 10.1093/nar/gkl946. Epub 2006 Nov 29.
5
Building a livestock genetic and genomic information knowledgebase through integrative developments of Animal QTLdb and CorrDB.通过动物 QTLdb 和 CorrDB 的综合开发,构建一个家畜遗传和基因组信息知识库。
Nucleic Acids Res. 2019 Jan 8;47(D1):D701-D710. doi: 10.1093/nar/gky1084.
6
Developmental progress and current status of the Animal QTLdb.动物数量性状基因座数据库的发展进程与现状
Nucleic Acids Res. 2016 Jan 4;44(D1):D827-33. doi: 10.1093/nar/gkv1233. Epub 2015 Nov 23.
7
The bovine QTL viewer: a web accessible database of bovine Quantitative Trait Loci.牛QTL浏览器:一个可通过网络访问的牛数量性状基因座数据库。
BMC Bioinformatics. 2006 Jun 5;7:283. doi: 10.1186/1471-2105-7-283.
8
Genome-wide in silico screening for microRNA genetic variability in livestock species.全基因组计算机筛选家畜物种中的 microRNA 遗传变异。
Anim Genet. 2013 Dec;44(6):669-77. doi: 10.1111/age.12072. Epub 2013 Jul 19.
9
Cotton QTLdb: a cotton QTL database for QTL analysis, visualization, and comparison between Gossypium hirsutum and G. hirsutum × G. barbadense populations.棉花QTL数据库:一个用于棉花QTL分析、可视化以及陆地棉与陆地棉×海岛棉群体间比较的棉花QTL数据库。
Mol Genet Genomics. 2015 Aug;290(4):1615-25. doi: 10.1007/s00438-015-1021-y. Epub 2015 Mar 11.
10
QTL MatchMaker: a multi-species quantitative trait loci (QTL) database and query system for annotation of genes and QTL.QTL匹配器:一个用于基因和数量性状基因座注释的多物种数量性状基因座(QTL)数据库及查询系统。
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D586-9. doi: 10.1093/nar/gkj027.

引用本文的文献

1
Advances in Genomics and Postgenomics in Poultry Science: Current Achievements and Future Directions.家禽科学中的基因组学和后基因组学进展:当前成就与未来方向。
Int J Mol Sci. 2025 Aug 26;26(17):8285. doi: 10.3390/ijms26178285.
2
A 17.1 kb duplication downstream GATA6 is strongly associated with egg weight in chicken.GATA6下游17.1 kb的重复与鸡的蛋重密切相关。
BMC Genomics. 2025 Aug 20;26(1):765. doi: 10.1186/s12864-025-11888-0.
3
Selection Signature Analysis of Whole-Genome Sequences to Identify Genome Differences Between Selected and Unselected Holstein Cattle.

本文引用的文献

1
Asking for more.要求更多。
Nat Genet. 2012 Jun 27;44(7):733. doi: 10.1038/ng.2345.
2
Three ontologies to define phenotype measurement data.三个本体定义表型测量数据。
Front Genet. 2012 May 28;3:87. doi: 10.3389/fgene.2012.00087. eCollection 2012.
3
Ensembl 2012.Ensembl 2012.
全基因组序列选择特征分析以鉴定选留与未选留荷斯坦奶牛之间的基因组差异
Animals (Basel). 2025 Jul 31;15(15):2247. doi: 10.3390/ani15152247.
4
Putative epigenetic regulation mechanisms related to production, carcass and beef quality traits in Nelore cattle.与内洛尔牛生产、胴体及牛肉品质性状相关的潜在表观遗传调控机制。
Front Genet. 2025 Jun 27;16:1593444. doi: 10.3389/fgene.2025.1593444. eCollection 2025.
5
Exploring genomic signatures of selection for adaptation and resilience in nomadic Belahi cattle in the tropical climate.探索热带气候下游牧贝拉希牛适应与恢复力的选择基因组特征。
Mol Biol Rep. 2025 Jul 7;52(1):676. doi: 10.1007/s11033-025-10793-9.
6
Genome-wide long non-coding RNA expression profile and its regulatory role in the ileocecal valve from subsp. -infected cattle.亚种感染牛回盲瓣的全基因组长链非编码RNA表达谱及其调控作用
Front Vet Sci. 2025 Jun 5;12:1601267. doi: 10.3389/fvets.2025.1601267. eCollection 2025.
7
Analysis of runs of homozygosity in Yeonsan Ogye chickens using 600K single nucleotide polymorphism arrays.利用600K单核苷酸多态性芯片分析临武鸭的纯合子片段
J Anim Sci Technol. 2025 May;67(3):520-535. doi: 10.5187/jast.2024.e11. Epub 2025 May 31.
8
Impact of Selection Signature on Genomic Prediction and Heritability Estimation in Livestock.选择印记对家畜基因组预测和遗传力估计的影响。
Animals (Basel). 2025 May 10;15(10):1383. doi: 10.3390/ani15101383.
9
Impact of different genomic relationship matrix construction methods on the accuracy of genomic prediction in different species.不同基因组关系矩阵构建方法对不同物种基因组预测准确性的影响。
Front Genet. 2025 May 2;16:1576248. doi: 10.3389/fgene.2025.1576248. eCollection 2025.
10
Identification of Gene Expression and Splicing QTLs in Porcine Muscle Associated with Meat Quality Traits.与肉质性状相关的猪肌肉中基因表达和剪接QTL的鉴定。
Animals (Basel). 2025 Apr 24;15(9):1209. doi: 10.3390/ani15091209.
Nucleic Acids Res. 2012 Jan;40(Database issue):D84-90. doi: 10.1093/nar/gkr991. Epub 2011 Nov 15.
4
Entrez Gene: gene-centered information at NCBI.Entrez基因:美国国立医学图书馆国家生物技术信息中心的基因中心信息。
Nucleic Acids Res. 2011 Jan;39(Database issue):D52-7. doi: 10.1093/nar/gkq1237. Epub 2010 Nov 28.
5
AnimalQTLdb: a livestock QTL database tool set for positional QTL information mining and beyond.动物数量性状基因座数据库:一个用于定位数量性状基因座信息挖掘及其他用途的家畜数量性状基因座数据库工具集。
Nucleic Acids Res. 2007 Jan;35(Database issue):D604-9. doi: 10.1093/nar/gkl946. Epub 2006 Nov 29.
6
A QTL resource and comparison tool for pigs: PigQTLDB.一种用于猪的QTL资源和比较工具:猪QTL数据库(PigQTLDB)。
Mamm Genome. 2005 Oct;16(10):792-800. doi: 10.1007/s00335-005-0060-9. Epub 2005 Oct 29.