Department of Radiology, Rheinische Friedrich-Wilhelms-University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany ; European Association for Predictive, Preventive & Personalised Medicine, Brussels, Belgium.
EPMA J. 2010 Jun;1(2):211-5. doi: 10.1007/s13167-010-0030-5. Epub 2010 Jun 29.
Current figures: About 300 million Diabetics frequently affected by Poly-Neuropathy as secondary complication, 18 million patients with Alzheimer's disease also diagnosed as Diabetes Type 3, neurodegenerative eye diseases with leading causes of blindness-diabetic retinopathy and estimated 67 million glaucoma patients worldwide, millions of patients with Parkinson's disease, Multiple Sclerosis, Epilepsy, Cerebral Palsy and Dementia in the elderly-altogether dramatically affect life quality, social and economical indexes of populations around the globe. Optimistic versus Pessimistic Prognosis depends much on diagnostic, preventive and treatment approaches which healthcare will preferably adopt in the near future. Without innovation in healthcare, neurodegenerative disorders can reach more than 30% of global disease burden till 2020. In contrast, effective utilisation of advanced early/predictive diagnostics, preventive and personalised medical approaches could enable a significant portion of population to reach the 100-year age limit remaining vibrant in excellent physical and mental health as actively contributing members of society.
约 3 亿糖尿病患者常受多发性神经病变等并发症影响，1800 万老年痴呆症患者也被诊断为 3 型糖尿病，退行性眼病是致盲的主要原因——糖尿病视网膜病变，全球约有 6700 万青光眼患者，数以百万计的帕金森病、多发性硬化症、癫痫、脑瘫和老年痴呆症患者——所有这些都严重影响了全球人口的生活质量、社会和经济指标。乐观还是悲观的预后在很大程度上取决于诊断、预防和治疗方法，而医疗保健在不久的将来最好采用这些方法。如果医疗保健没有创新，到 2020 年，神经退行性疾病的负担可能会占到全球疾病负担的 30%以上。相比之下，如果能够有效利用先进的早期/预测性诊断、预防和个性化医疗方法，就有可能使相当一部分人达到 100 岁的寿命极限，保持身心健康，活力充沛，积极作为社会的活跃成员。
