Division of Surgery, Department of Surgery and Cancer, Imperial College London, St Mary's Hospital, London, United Kingdom.
Semin Thorac Cardiovasc Surg. 2012 Autumn;24(3):176-87. doi: 10.1053/j.semtcvs.2012.10.004.
Minimally invasive esophagectomy (MIE) has been increasingly performed to treat esophageal cancer. Studies published between 1990 and 2012 that described the use of MIE for cancer in at least 50 patients were included for systematic review. The literature search retrieved 34 publications comprising 18 case series, 15 comparative studies, and 1 randomized control trial. Results revealed a wide variability in surgical techniques and perioperative outcomes with a lack of standardized definitions of postoperative complications. In most studies, radical formal lymphadenectomy was not performed and the lymph node harvest fell below the minimum number recommended to achieve survival benefits. There is a need to reach a consensus regarding surgical approaches in MIE, the definition of postoperative complications and the extent of lymphadenectomy before embarking on further randomized controlled trials comparing MIE vs. open approach.
微创食管切除术（MIE）已被越来越多地用于治疗食管癌。纳入了 1990 年至 2012 年间至少 50 例患者使用 MIE 治疗癌症的研究进行系统评价。文献检索检索到 34 篇出版物，包括 18 个病例系列，15 个对照研究和 1 个随机对照试验。结果显示，手术技术和围手术期结果存在很大差异，并且缺乏对术后并发症的标准化定义。在大多数研究中，没有进行根治性正规淋巴结清扫术，淋巴结采集量低于获得生存益处所需的最低数量。在进行进一步比较 MIE 与开放方法的随机对照试验之前，有必要就 MIE 中的手术方法、术后并发症的定义和淋巴结清扫范围达成共识。
