Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, USA.
Epilepsy Behav. 2013 Jan;26(1):25-8. doi: 10.1016/j.yebeh.2012.10.022. Epub 2012 Nov 30.
Impaired consciousness in epilepsy has a significant negative impact on patients' quality of life yet is difficult to study objectively. Here, we develop an improved prospective Responsiveness in Epilepsy Scale-II (RES-II) and report initial results compared with the earlier version of the scale (RES). The RES-II is simpler to administer and includes both verbal and non-verbal test items. We evaluated 75 seizures (24 patients) with RES and 34 seizures (11 patients) with RES-II based on video-EEG review. The error rate per seizure by test administrators improved markedly from a mean of 2.01 ± 0.04 with RES to 0.24 ± 0.11 with RES-II. Performance during focal seizures showed a bimodal distribution, corresponding to the traditional complex partial vs. simple partial seizure classification. We conclude that RES-II has improved accuracy and testing efficiency compared with the original RES. Prospective objective testing will ultimately lead to a better understanding of the mechanisms of impaired consciousness in epilepsy.
癫痫意识障碍对患者的生活质量有重大负面影响，但难以客观研究。在这里，我们开发了一种改良的前瞻性癫痫反应性量表-II（RES-II），并报告了与早期版本量表（RES）的初步结果比较。RES-II 更易于管理，并且包括口头和非口头测试项目。我们根据视频-EEG 回顾评估了 75 次癫痫发作（24 例患者）和 34 次癫痫发作（11 例患者），RES 和 RES-II 的每个癫痫发作的错误率从平均 2.01±0.04 显著改善至 0.24±0.11。局灶性发作期间的表现呈双峰分布，与传统的复杂部分性 vs. 单纯部分性发作分类相对应。我们得出结论，RES-II 与原始 RES 相比，准确性和测试效率都有所提高。前瞻性客观测试最终将有助于更好地理解癫痫意识障碍的机制。
