基于 Eudragit 涂层声回廊模式谐振器的免疫传感器的性能。
Performance of Eudragit coated whispering gallery mode resonator-based immunosensors.
机构信息
Istituto di Fisica Applicata Nello Carrara (IFAC CNR), 50019 Sesto Fiorentino, Firenze, Italy.
出版信息
Sensors (Basel). 2012 Oct 30;12(11):14604-11. doi: 10.3390/s121114604.
Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.
whispering gallery mode resonators (WGMR) 是实现光学生物传感器的有效工具。保持高 Q 因子是获得良好生物传感器性能的关键要求。在这项工作中，我们展示了一种 Eudragit®L100 涂层微球 WGMR 作为一种有效的免疫传感器。使用荧光显微镜对开发的谐振器进行了形态学表征。对功能化过程进行了调整，以保持谐振器的高 Q 因子。在缓冲溶液中，从特异性的角度对蛋白质结合测定进行了光学表征。
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