Department of Environmental Health Science, Nara Women's University, Kita-Uoya Nishimachi, Nara 630-8506, Japan.
J Oncol. 2012;2012:236530. doi: 10.1155/2012/236530. Epub 2012 Nov 20.
Cancer remains a major cause of death, although research is ongoing for the development of more effective drugs. Some herbs have shown potential in preventing the occurrence and/or progression of cancer and other chronic diseases. They are being screened comprehensively to explore the possibility of development of feasible anticancer drugs. However, more information is required about the response to and the molecular target for specific herbs. It seems that there is a relationship between some medicinal herbs and tumor suppressor molecules which protect a cell from cancer. In this paper, we summarize the progress of recent research on herbs, with a particular focus on its anticancer role and molecular mechanisms underlying the cancer prevention property, supporting design for further research in this field.
癌症仍然是主要的死亡原因，尽管正在进行研究以开发更有效的药物。一些草药在预防癌症和其他慢性疾病的发生和/或进展方面显示出潜力。正在对它们进行全面筛选，以探索开发可行抗癌药物的可能性。然而，需要更多关于特定草药的反应和分子靶标的信息。似乎一些草药与肿瘤抑制分子之间存在关系，这些分子可以保护细胞免受癌症侵害。在本文中，我们总结了最近关于草药的研究进展，特别关注其抗癌作用和预防癌症的分子机制，为该领域的进一步研究提供了设计依据。
