Department of Speech-Language-Hearing Sciences, University of Minnesota, USA.
J Child Lang. 2013 Jan;40(1):244-65. doi: 10.1017/S0305000912000207.
ABSTRACT This study compared the receptive and expressive language profiles of verbally expressive children and adolescents with Down Syndrome (DS) and those with Fragile X syndrome (FXS) and examined the extent to which these profiles reliably differentiate the diagnostic groups. A total of twenty-four verbal participants with DS (mean age: 12 years), twenty-two verbal participants with FXS (mean age: 12 years), and twenty-seven participants with typical development (TD; mean age = 4 years) completed standardized measures of receptive and expressive vocabulary and grammar, as well as a conversational language sample. Study results indicate that there are distinct DS and FXS language profiles, which are characterized by differences in grammatical ability. The diagnostic groups were not differentiated based on vocabulary performance. This study supports the existence of unique language profiles associated with DS and FXS.
摘要 本研究比较了表达性语言能力正常的唐氏综合征（DS）儿童和青少年与脆性 X 综合征（FXS）儿童和青少年的接受性和表达性语言特征，并探讨了这些特征在多大程度上能够可靠地区分诊断组。共有 24 名具有表达性语言能力的 DS 儿童（平均年龄：12 岁）、22 名具有表达性语言能力的 FXS 儿童（平均年龄：12 岁）和 27 名具有典型发育的儿童（TD；平均年龄=4 岁）完成了标准化的接受性和表达性词汇和语法测试，以及会话语言样本。研究结果表明，存在明显的 DS 和 FXS 语言特征，其特点是语法能力存在差异。诊断组不能根据词汇表现进行区分。本研究支持与 DS 和 FXS 相关的独特语言特征的存在。
