鼠肉瘤病毒基因在遭受无氧应激的未感染大鼠细胞中的表达。
Expression of murine sarcoma virus genes in uninfected rat cells subjected to anaerobic sress.
作者信息
Anderson G R, Matovcik L M
出版信息
Science. 1977 Sep 30;197(4311):1371-4. doi: 10.1126/science.197602.
PMID:197602
Abstract
Exposure of uninfected rat cells in tissue culture to anaerobic culture conditions induces transcription of RNA corresponding to the two principal constituents of rat-derived type-C sarcoma virus genomes: (i) those specific rat cell sequences present in the Kirsten and Harvey murine sarcoma virus genomes, and (ii) an endogenous type-C rat leukemia virus.
摘要
在组织培养中，将未感染的大鼠细胞暴露于厌氧培养条件下，可诱导与大鼠源C型肉瘤病毒基因组的两个主要成分相对应的RNA转录：（i）存在于克氏和哈维小鼠肉瘤病毒基因组中的那些特定大鼠细胞序列，以及（ii）一种内源性C型大鼠白血病病毒。
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