电生理低频相干和跨频耦合有助于 BOLD 连接。
Electrophysiological low-frequency coherence and cross-frequency coupling contribute to BOLD connectivity.
机构信息
Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
出版信息
Neuron. 2012 Dec 6;76(5):1010-20. doi: 10.1016/j.neuron.2012.09.033.
Abstract
Brain networks are commonly defined using correlations between blood oxygen level-dependent (BOLD) signals in different brain areas. Although evidence suggests that gamma-band (30-100 Hz) neural activity contributes to local BOLD signals, the neural basis of interareal BOLD correlations is unclear. We first defined a visual network in monkeys based on converging evidence from interareal BOLD correlations during a fixation task, task-free state, and anesthesia, and then simultaneously recorded local field potentials (LFPs) from the same four network areas in the task-free state. Low-frequency oscillations (<20 Hz), and not gamma activity, predominantly contributed to interareal BOLD correlations. The low-frequency oscillations also influenced local processing by modulating gamma activity within individual areas. We suggest that such cross-frequency coupling links local BOLD signals to BOLD correlations across distributed networks.
摘要
脑网络通常使用不同脑区血氧水平依赖 (BOLD) 信号之间的相关性来定义。尽管有证据表明，γ 波段 (30-100 Hz) 神经活动有助于局部 BOLD 信号，但区域间 BOLD 相关性的神经基础尚不清楚。我们首先根据在固定任务、无任务状态和麻醉期间区域间 BOLD 相关性的综合证据，在猴子中定义了一个视觉网络，然后在无任务状态下同时记录来自相同四个网络区域的局部场电位 (LFP)。低频振荡（<20 Hz）而不是 γ 活动，主要导致区域间 BOLD 相关性。低频振荡还通过调制单个区域内的 γ 活动来影响局部处理。我们认为，这种跨频耦合将局部 BOLD 信号与分布式网络之间的 BOLD 相关性联系起来。
相似文献
1
Electrophysiological low-frequency coherence and cross-frequency coupling contribute to BOLD connectivity.电生理低频相干和跨频耦合有助于 BOLD 连接。
Neuron. 2012 Dec 6;76(5):1010-20. doi: 10.1016/j.neuron.2012.09.033.
2
Crosslinking EEG time-frequency decomposition and fMRI in error monitoring.在错误监测中交联脑电图时频分解与功能磁共振成像
Brain Struct Funct. 2014 Mar;219(2):595-605. doi: 10.1007/s00429-013-0521-y. Epub 2013 Feb 27.
3
Quasi-periodic patterns (QPP): large-scale dynamics in resting state fMRI that correlate with local infraslow electrical activity.准周期模式（QPP）：静息态 fMRI 中的大尺度动力学，与局部亚慢电活动相关。
Neuroimage. 2014 Jan 1;84:1018-31. doi: 10.1016/j.neuroimage.2013.09.029. Epub 2013 Sep 23.
4
Neural correlates of time-varying functional connectivity in the rat.大鼠中时变功能连接的神经相关物。
Neuroimage. 2013 Dec;83:826-36. doi: 10.1016/j.neuroimage.2013.07.036. Epub 2013 Jul 19.
5
The contribution of different frequency bands of fMRI data to the correlation with EEG alpha rhythm.功能磁共振成像数据的不同频带对与脑电图阿尔法节律相关的贡献。
Brain Res. 2014 Jan 16;1543:235-43. doi: 10.1016/j.brainres.2013.11.016. Epub 2013 Nov 22.
6
Neuronal dynamics underlying high- and low-frequency EEG oscillations contribute independently to the human BOLD signal.高、低频 EEG 振荡背后的神经元动力学独立贡献于人类 BOLD 信号。
Neuron. 2011 Feb 10;69(3):572-83. doi: 10.1016/j.neuron.2010.11.044.
7
The change of functional connectivity specificity in rats under various anesthesia levels and its neural origin.不同麻醉深度下大鼠功能连接特异性的变化及其神经起源。
Brain Topogr. 2013 Jul;26(3):363-77. doi: 10.1007/s10548-012-0267-5. Epub 2012 Dec 4.
8
Inter-individual differences in resting-state functional connectivity predict task-induced BOLD activity.静息态功能连接的个体间差异可预测任务诱发的 BOLD 活动。
Neuroimage. 2010 May 1;50(4):1690-701. doi: 10.1016/j.neuroimage.2010.01.002. Epub 2010 Jan 15.
9
BOLD fractional contribution to resting-state functional connectivity above 0.1 Hz.高于0.1 Hz时，静息态功能连接的血氧水平依赖分数贡献。
Neuroimage. 2015 Feb 15;107:207-218. doi: 10.1016/j.neuroimage.2014.12.012. Epub 2014 Dec 12.
10
Relationships between correlated spikes, oxygen and LFP in the resting-state primate.静息状态下灵长类动物中相关尖峰、氧和 LFP 之间的关系。
Neuroimage. 2022 Feb 15;247:118728. doi: 10.1016/j.neuroimage.2021.118728. Epub 2021 Dec 16.
引用本文的文献
1
Rest assured: Dynamic functional connectivity and the baseline state of the human brain.放心：人类大脑的动态功能连接性与基线状态。
Imaging Neurosci (Camb). 2024 Nov 19;2. doi: 10.1162/imag_a_00365. eCollection 2024.
2
Flicker light stimulation induces thalamocortical hyperconnectivity with LGN and higher-order thalamic nuclei.闪烁光刺激诱导丘脑皮质与外侧膝状体及丘脑高级核团之间的高连接性。
Imaging Neurosci (Camb). 2023 Nov 23;1. doi: 10.1162/imag_a_00033. eCollection 2023.
3
Bridging local and global dynamics: a biologically grounded model for cooperative and competitive interactions in the brain.连接局部与全局动态：一个基于生物学的大脑中合作与竞争相互作用模型。
bioRxiv. 2025 Jul 14:2025.07.09.663817. doi: 10.1101/2025.07.09.663817.
4
Thalamocortical interactions reflecting the intensity of flicker light-induced visual hallucinatory phenomena.反映闪烁光诱导的视觉幻觉现象强度的丘脑皮质相互作用。
Netw Neurosci. 2025 Mar 3;9(1):1-17. doi: 10.1162/netn_a_00417. eCollection 2025.
5
Coupled oscillations orchestrate selective information transmission in visual cortex.耦合振荡协调视觉皮层中的选择性信息传递。
PNAS Nexus. 2024 Jul 31;3(8):pgae288. doi: 10.1093/pnasnexus/pgae288. eCollection 2024 Aug.
6
The neural basis of resting-state fMRI functional connectivity in fronto-limbic circuits revealed by chemogenetic manipulation.通过化学遗传学操作揭示额 - 边缘回路静息态 fMRI 功能连接的神经基础。
Nat Commun. 2024 May 31;15(1):4669. doi: 10.1038/s41467-024-49140-0.
7
Mapping and comparing fMRI connectivity networks across species.在物种间绘制和比较 fMRI 连接网络。
Commun Biol. 2023 Dec 7;6(1):1238. doi: 10.1038/s42003-023-05629-w.
8
Neuromodulation of striatal D1 cells shapes BOLD fluctuations in anatomically connected thalamic and cortical regions.纹状体 D1 细胞的神经调节塑造了与解剖连接的丘脑和皮层区域的 BOLD 波动。
Elife. 2023 Oct 12;12:e78620. doi: 10.7554/eLife.78620.
9
Temporospatial Nestedness in Consciousness: An Updated Perspective on the Temporospatial Theory of Consciousness.意识中的时空嵌套性：意识时空理论的更新视角
Entropy (Basel). 2023 Jul 17;25(7):1074. doi: 10.3390/e25071074.
10
Identifying the distinct spectral dynamics of laminar-specific interhemispheric connectivity with bilateral line-scanning fMRI.利用双边线扫描 fMRI 识别层特异性大脑两半球间连通性的独特光谱动态。
J Cereb Blood Flow Metab. 2023 Jul;43(7):1115-1129. doi: 10.1177/0271678X231158434. Epub 2023 Feb 21.
本文引用的文献
1
The pulvinar regulates information transmission between cortical areas based on attention demands.丘脑后结节根据注意力需求调节皮质区域之间的信息传递。
Science. 2012 Aug 10;337(6095):753-6. doi: 10.1126/science.1223082.
2
Spontaneous high-gamma band activity reflects functional organization of auditory cortex in the awake macaque.自发性高频γ带活动反映了清醒猕猴听觉皮层的功能组织。
Neuron. 2012 Jun 7;74(5):899-910. doi: 10.1016/j.neuron.2012.04.014.
3
Mechanisms of gamma oscillations.γ 振荡的机制。
Annu Rev Neurosci. 2012;35:203-25. doi: 10.1146/annurev-neuro-062111-150444. Epub 2012 Mar 20.
4
An oscillatory mechanism for prioritizing salient unattended stimuli.一种用于优先处理突出的未被注意刺激的振荡机制。
Trends Cogn Sci. 2012 Apr;16(4):200-6. doi: 10.1016/j.tics.2012.03.002. Epub 2012 Mar 19.
5
Rat brains also have a default mode network.大鼠大脑也有一个默认模式网络。
Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3979-84. doi: 10.1073/pnas.1200506109. Epub 2012 Feb 21.
6
The amplitude and timing of the BOLD signal reflects the relationship between local field potential power at different frequencies.BOLD 信号的幅度和时间反映了不同频率局部场电位功率之间的关系。
J Neurosci. 2012 Jan 25;32(4):1395-407. doi: 10.1523/JNEUROSCI.3985-11.2012.
7
Spectral fingerprints of large-scale neuronal interactions.大规模神经元相互作用的光谱指纹。
Nat Rev Neurosci. 2012 Jan 11;13(2):121-34. doi: 10.1038/nrn3137.
8
How local is the local field potential?局部场电位有多局部？
Neuron. 2011 Dec 8;72(5):847-58. doi: 10.1016/j.neuron.2011.09.029.
9
A 4 Hz oscillation adaptively synchronizes prefrontal, VTA, and hippocampal activities.4 Hz 脑电波振荡自适应地同步前额叶皮层、腹侧被盖区和海马体的活动。
Neuron. 2011 Oct 6;72(1):153-65. doi: 10.1016/j.neuron.2011.08.018.
10
Functional roles of alpha-band phase synchronization in local and large-scale cortical networks.alpha 波段相位同步在局部和大规模皮质网络中的功能作用。
Front Psychol. 2011 Sep 5;2:204. doi: 10.3389/fpsyg.2011.00204. eCollection 2011.
Zotero 插件