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飞秒激光白内障手术的手术效果和安全性:1500 例连续病例的前瞻性研究。

Surgical outcomes and safety of femtosecond laser cataract surgery: a prospective study of 1500 consecutive cases.

机构信息

Vision Eye Institute, Chatswood, Australia.

出版信息

Ophthalmology. 2013 Feb;120(2):227-33. doi: 10.1016/j.ophtha.2012.10.026. Epub 2012 Dec 6.

Abstract

OBJECTIVE

To report the surgical outcomes and safety of femtosecond (FS) laser cataract surgery (LCS) with greater surgeon experience, modified techniques, and improved technology.

DESIGN

Prospective, interventional case series.

PARTICIPANTS

Fifteen hundred consecutive eyes undergoing FS laser cataract and refractive lens exchange surgery in a single group private practice.

INTERVENTION

Femtosecond LCS.

METHODS

All eyes undergoing LCS between April 2011 and March 2012 were included in the study. Cases underwent anterior capsulotomy, lens fragmentation, and corneal incisions with the Alcon/LenSx FS laser (Alcon/LenSx, Aliso Viejo, CA). The procedure was completed by phacoemulsification and insertion of an intraocular lens. The cases were divided into 2 groups: Group 1, initial experience consisting of the first 200 cases; and group 2, the subsequent 1300 cases performed by the same surgeons.

MAIN OUTCOME MEASURES

Intraoperative complication rates and comparison between groups.

RESULTS

Both groups were comparable for baseline demographic parameters. Anterior capsule tears occurred in 4% and 0.31% of eyes, posterior capsule tears in 3.5% and 0.31% of eyes, and posterior lens dislocation in 2% and 0% of eyes in groups 1 group 2, respectively (P<0.001 for all comparisons). Number of docking attempts per case (1.5 vs 1.05), incidence of post-laser pupillary constriction (9.5% vs 1.23%), and anterior capsular tags (10.5% vs 1.61%) were significantly lower in group 2 (P<0.001 for all comparisons).

CONCLUSIONS

In the authors' experience, the surgical outcomes and safety of LCS improved significantly with greater surgeon experience, development of modified techniques, and improved technology.

摘要

目的

报告随着外科医生经验的增加、手术技术的改良和设备的改进,飞秒(FS)激光白内障手术(LCS)的手术效果和安全性。

设计

前瞻性、干预性病例系列研究。

参与者

在一个单一的私人执业小组中,1500 只连续进行 FS 激光白内障和屈光性晶状体置换手术的眼睛。

干预措施

FS LCS。

方法

所有在 2011 年 4 月至 2012 年 3 月期间接受 LCS 的病例均纳入研究。这些病例接受了前囊切开术、晶状体碎核术和角膜切口术,使用的是 Alcon/LenSx FS 激光(Alcon/LenSx,Aliso Viejo,CA)。该手术由超声乳化术和人工晶状体插入术完成。这些病例被分为两组:第 1 组,初始经验组,包括前 200 例;第 2 组,由同一位外科医生进行的随后的 1300 例。

主要观察指标

术中并发症发生率和组间比较。

结果

两组在基线人口统计学参数方面具有可比性。第 1 组和第 2 组的眼睛发生前囊撕裂的比例分别为 4%和 0.31%,后囊撕裂的比例分别为 3.5%和 0.31%,后发性晶状体脱位的比例分别为 2%和 0%(所有比较均 P<0.001)。每例手术的对接尝试次数(1.5 次比 1.05 次)、激光后瞳孔收缩的发生率(9.5%比 1.23%)和前囊标签的发生率(10.5%比 1.61%)在第 2 组均显著降低(所有比较均 P<0.001)。

结论

在作者的经验中,随着外科医生经验的增加、手术技术的改良和设备的改进,LCS 的手术效果和安全性显著提高。

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