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德国巴伐利亚州通过室内灰尘摄入全氟辛烷磺酸、全氟辛酸及其醇类物质的人体暴露量

Human exposure to fluorotelomer alcohols, perfluorooctane sulfonate and perfluorooctanoate via house dust in Bavaria, Germany.

机构信息

Helmholtz Center Munich - National Research Center for Environmental Health, Molecular EXposomics (MEX), Ingolstädter Landstr.1, Neuherberg 85764, Germany.

出版信息

Sci Total Environ. 2013 Jan 15;443:485-90. doi: 10.1016/j.scitotenv.2012.10.089. Epub 2012 Dec 4.

Abstract

This study aimed at investigating the presence and distribution of fluorotelomer alcohols (FTOHs), perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in house dust to evaluate human exposure to these compounds via dust ingestion. 31 house dust samples were collected from Bavaria, Germany and analyzed for 4:2, 6:2, 8:2 and 10:2 FTOH, PFOS and PFOA. PFOA was the dominant compound in 79% of the dust samples, followed by PFOS and 8:2 FTOH, while 4:2 FTOH was not detected in any samples. The total concentration of per- and polyfluorinated compounds (PFCs) varied from 32.2 to 2456 ng/g. In addition, the total ingestion rate for PFCs was 0.4-135 ng/d for adults and 5.1-246 ng/d for toddlers, and the highest 8:2 FTOH-based PFOA intake via indoor dust was 0.24 ng/d for adults and 0.44 ng/d for toddlers. Overall, the results of this study demonstrate that dust ingestion is a minor pathway for human exposure to these PFCs; the PFC ingestion via indoor dust is generally low, and only under a worst scenario high intakes have to be expected for toddlers.

摘要

本研究旨在调查房屋灰尘中氟调聚物醇(FTOHs)、全氟辛烷磺酸(PFOS)和全氟辛酸(PFOA)的存在和分布情况,以评估人类通过灰尘摄入接触这些化合物的情况。从德国巴伐利亚州采集了 31 个房屋灰尘样本,并对其进行了 4:2、6:2、8:2 和 10:2 FTOH、PFOS 和 PFOA 的分析。在 79%的灰尘样本中,PFOA 是主要化合物,其次是 PFOS 和 8:2 FTOH,而 4:2 FTOH 在任何样本中均未检测到。全氟和多氟化合物(PFCs)的总浓度从 32.2 到 2456 ng/g 不等。此外,成年人的 PFC 总摄入率为 0.4-135ng/d,幼儿为 5.1-246ng/d,通过室内灰尘摄入的基于 8:2 FTOH 的 PFOA 最高摄入量为成年人 0.24ng/d,幼儿 0.44ng/d。总体而言,本研究结果表明,灰尘摄入是人类接触这些 PFCs 的次要途径;通过室内灰尘摄入的 PFC 摄入量通常较低,只有在最坏的情况下,幼儿才会有高摄入量。

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