R&D Laboratories, Self Medication Business, Taisho Pharmaceutical Co. Ltd, 403, Yoshino-cho 1-chome, Kita-ku, Saitama-shi, Saitama, 331-9530, Japan.
Amino Acids. 2014 Jan;46(1):81-8. doi: 10.1007/s00726-012-1434-4. Epub 2012 Dec 8.
Metabolic syndrome is characterized by the cluster of a number of metabolic abnormalities in the presence of underlying insulin resistance. The prevalence of metabolic syndrome has steadily increased in all populations worldwide. Taurine (2-aminoethanesulfonic acid) is a sulfur-containing amino acid that is involved in a variety of physiological functions. Clinical and experimental studies show that taurine intake may be beneficial in the prevention of metabolic syndrome including diabetes, obesity, dyslipidemia, and hypertension. This article reviews the effect of taurine on all of the components of metabolic syndrome. In addition, the possible mechanisms by which taurine prevents diabetes and metabolic syndrome are also discussed. Further study is needed to determine the role of taurine in the development of metabolic syndrome in humans, because there is presently limited clinical data available.
代谢综合征的特征是在存在潜在胰岛素抵抗的情况下出现多种代谢异常。代谢综合征在全球所有人群中的患病率都在稳步上升。牛磺酸（2-氨基乙磺酸）是一种含硫氨基酸，参与多种生理功能。临床和实验研究表明，牛磺酸的摄入可能有益于预防代谢综合征，包括糖尿病、肥胖、血脂异常和高血压。本文综述了牛磺酸对代谢综合征所有成分的影响。此外，还讨论了牛磺酸预防糖尿病和代谢综合征的可能机制。由于目前可获得的临床数据有限，需要进一步的研究来确定牛磺酸在人类代谢综合征发展中的作用。
