Dubois James, Bante Holly, Hadley Whitney B
Saint Louis University - Gnaegi Center for Health Care Ethics, 221 North Grand Blvd, St. Louis, Missouri 63103,
AJOB Prim Res. 2011 Jan 1;2(4):5-17. doi: 10.1080/21507716.2011.631514. Epub 2011 Dec 6.
This paper reviews the past 25 years of empirical research funded by the National Institutes of Health (NIH) on matters of ethics in psychiatric research. METHODS: Using the NIH RePORTER and Medline databases, we identified 43 grants and 77 publications that involved the empirical study of a matter of ethics in research involving mental health service users. RESULTS: These articles provide original and useful information on important topics, most especially the capacity to consent and the voluntariness of consent. For example, participants who share a diagnosis vary widely in levels of cognitive impairment that correlate with decisional capacity, and capacity to consent can be enhanced easily using iterative consent processes. Few articles address matters of justice or benefits in research, particularly from the perspectives of participants. No articles address matters of privacy, confidentiality, or researcher professionalism. CONCLUSIONS: Despite the usefulness of data from the studies conducted to date, current research on research ethics in psychiatry does not adequately address the concerns of service users as expressed in recent publications.
本文回顾了美国国立卫生研究院（NIH）在过去25年里资助的关于精神科研究伦理问题的实证研究。方法：利用NIH RePORTER和Medline数据库，我们识别出43项资助项目和77篇出版物，这些研究涉及对涉及精神卫生服务使用者的研究中的伦理问题进行实证研究。结果：这些文章提供了关于重要主题的原创且有用的信息，尤其是同意的能力和同意的自愿性。例如，患有相同诊断的参与者在与决策能力相关的认知障碍水平上差异很大，并且使用迭代同意程序可以很容易地提高同意能力。很少有文章涉及研究中的公正或利益问题，特别是从参与者的角度。没有文章涉及隐私、保密或研究者专业性的问题。结论：尽管迄今为止进行的研究数据有用，但目前关于精神科研究伦理的研究并未充分解决近期出版物中所表达的服务使用者的担忧。
