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在急诊科切开引流后,使用含银水凝胶纤维敷料填塞脓肿腔:一项随机对照试验。

Use of a silver-containing hydrofiber dressing for filling abscess cavity following incision and drainage in the emergency department: a randomized controlled trial.

机构信息

Department of Emergency Medicine, Maricopa Medical Center, Phoenix, Arizona, USA.

出版信息

Adv Skin Wound Care. 2013 Jan;26(1):20-5. doi: 10.1097/01.ASW.0000425936.94874.9a.

Abstract

OBJECTIVE

The objective of this study was to investigate whether the use of a silver-containing hydrofiber dressing to pack abscess cavity after incision and drainage (I & D) leads to faster wound healing and less pain.

METHODS

Patients 18 years or older visiting the emergency department with cutaneous abscesses, requiring I & D, were randomly assigned to the intervention (Aquacel Ag; ConvaTec, Skillman, New Jersey) or standard care (iodoform) group between April 2008 and May 2009. Patients were followed up 48 to 72 hours and 10 to 14 days after the initial visit. Primary outcomes were the proportion of patients with greater than 30% reduction in surface area of abscess or cellulitis at first follow-up.

RESULTS

Ninety-two patients were enrolled prospectively and randomly assigned to the Aquacel Ag or the iodoform groups; mean age was 38.0 (SD, 12.0) years; 49 patients were in the Aquacel Ag and 43 were in iodoform groups, respectively. There were no differences in demographic and clinical characteristics between groups. Logistic regression analysis showed that the intervention (Aquacel Ag) was independently associated with greater than 30% reduction in surface area of abscess (P = .002) but not in cellulitis at first follow-up. There was also significant decrease in pain intensity perceived by patients in the Aquacel Ag group based on the mean change in Facial Pain Scale scores between the initial visit and first follow-up.

CONCLUSION

In patients with cutaneous abscesses, use of an antimicrobial hydrofiber ribbon dressing for packing was associated with faster wound healing and reduction in perceived pain in comparison with use of iodoform dressing.

摘要

目的

本研究旨在探讨在切开引流(I&D)后使用含银水凝胶纤维敷料填塞脓肿腔是否能促进更快的伤口愈合和减轻疼痛。

方法

2008 年 4 月至 2009 年 5 月,对因皮肤脓肿需行 I&D 的 18 岁及以上急诊科患者,采用随机分组法将其分为干预组(Aquacel Ag;康维德,新泽西州斯克里尔曼)和标准护理组(碘仿)。患者在初次就诊后 48 至 72 小时和 10 至 14 天进行随访。主要结局是初次随访时脓肿或蜂窝织炎表面面积减少 30%以上的患者比例。

结果

92 例患者前瞻性纳入并随机分配至 Aquacel Ag 组或碘仿组;平均年龄为 38.0(标准差,12.0)岁;分别有 49 例和 43 例患者进入 Aquacel Ag 组和碘仿组。两组间人口统计学和临床特征无差异。逻辑回归分析显示,干预(Aquacel Ag)与脓肿表面面积减少 30%以上独立相关(P =.002),但与初次随访时蜂窝织炎无关。根据初次就诊和初次随访时面部疼痛量表评分的平均变化,Aquacel Ag 组患者的疼痛强度也显著降低。

结论

与使用碘仿敷料相比,在皮肤脓肿患者中,使用含抗菌水凝胶纤维带敷料填塞可促进更快的伤口愈合并减轻疼痛感知。

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