Department of Burns and Plastic Surgery, The Hospital Affiliated to Jiangsu Universitity, Zhenjiang, Jiangsu Province 212001, PR China.
Burns. 2013 Dec;39(8):1547-50. doi: 10.1016/j.burns.2013.04.017. Epub 2013 Aug 29.
This study was conducted to compare pain, healing time, infection rate, and cosmetic outcome between Aquacel Ag (convatec) and Alginate Silver (coloplast) as donor site dressings.
We conducted a prospective randomized controlled trial of donor site dressings, comparing Aquacel Ag with Alginate Silver. Patients were randomly allocated to donor site dressing with one of these materials. Outcome measures included pain scores at rest and during dressing changes, time to re-epithelialization, cosmetic outcome and infection rate. Results were assessed for significance using the independent t-test (non-parametric data) and the chi-square test (parametric data).
A total of 20 subjects were enrolled in this study. Subjects included in both groups were comparable with no significant differences in demographic data of age, gender, location of burn and type of burns (P > 0.05 evaluated by paired t-test) between both group. The pain scores were found to be higher in Aquacel Ag group than in Alginate Silver group. Time to re-epithelialization was longer in Aquacel Ag group than in Alginate Silver group. There were no significant differences between the two treatment groups with respect to cosmetic outcome and infection rate.
Based on these results, we find that Alginate Silver is better than Aquacel Ag to cover the skin graft donor site.
本研究旨在比较水凝胶银(康维德)和藻酸钙银(康乐保)作为供皮区敷料在疼痛、愈合时间、感染率和美容效果方面的差异。
我们进行了一项供皮区敷料的前瞻性随机对照试验,比较了水凝胶银和藻酸钙银。将患者随机分配到使用其中一种材料的供皮区敷料。主要观察指标包括静息和换药时的疼痛评分、上皮再形成时间、美容效果和感染率。采用独立 t 检验(非参数数据)和卡方检验(参数数据)评估结果的统计学意义。
共有 20 例患者纳入本研究。两组患者的年龄、性别、烧伤部位和烧伤类型等人口统计学数据无显著差异(配对 t 检验,P > 0.05)。水凝胶银组的疼痛评分高于藻酸钙银组。水凝胶银组上皮再形成时间长于藻酸钙银组。两组在美容效果和感染率方面无显著差异。
基于这些结果,我们发现藻酸钙银比水凝胶银更适合覆盖皮肤移植供皮区。