Dpto. Citología e Histología Normal y Patológica, Facultad de Medicina, Universidad de Sevilla, Avda. Sánchez-Pizjuán s/n, 41009, Sevilla, Spain,
Rheumatol Int. 2014 Mar;34(3):419-22. doi: 10.1007/s00296-012-2647-2. Epub 2013 Jan 3.
In order to analyze the association between body mass index (BMI), lipid profile and clinical symptoms in patients with fibromyalgia, we assessed BMI levels, lipid profile and its association with clinical symptoms in 183 patients with fibromyalgia. The patients were evaluated using tender points, FIQ and Visual Analogue Scales of pain (VAS). Serum lipid profile analysis (total cholesterol, triglyceride, HDL, LDL and VLDL), and biochemical parameters were measured in the biochemistry laboratory. The BMI distribution of the nonobese, overweight and obese patients' groups were relatively even with 37.7, 35.5 and 26.8%, respectively, with a mean BMI of 27.3 ± 4.9. The number of tender points showed significantly positive correlation with higher BMI (P < 0.05). A total of 57.9% of patients showed increased levels of total cholesterol, 63.4 % increased levels of LDL cholesterol and 19.9% high levels of triglycerides. BMI, total cholesterol and triglycerides showed high association with some clinical parameters. Overweight and lipid profile could be associated with fibromyalgia symptoms. A treatment program with weight loss strategies, and control in diet and increased physical activity is advised to patients.
为了分析身体质量指数（BMI）、血脂谱与纤维肌痛患者临床症状之间的关系，我们评估了 183 例纤维肌痛患者的 BMI 水平、血脂谱及其与临床症状的关系。采用压痛点、FIQ 和疼痛视觉模拟量表（VAS）对患者进行评估。在生化实验室测量血清脂质谱分析（总胆固醇、甘油三酯、HDL、LDL 和 VLDL）和生化参数。非肥胖、超重和肥胖患者组的 BMI 分布相对均匀，分别为 37.7%、35.5%和 26.8%，平均 BMI 为 27.3±4.9。压痛点数与较高的 BMI 呈显著正相关（P<0.05）。总胆固醇升高的患者占 57.9%，LDL 胆固醇升高的患者占 63.4%，甘油三酯升高的患者占 19.9%。BMI、总胆固醇和甘油三酯与一些临床参数高度相关。超重和血脂谱可能与纤维肌痛症状有关。建议患者采用减肥策略、控制饮食和增加体育锻炼的治疗方案。
