• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一种用于区分半胱氨酸、同型半胱氨酸和谷胱甘肽的荧光传感器。

A turn-on fluorescent sensor for the discrimination of cystein from homocystein and glutathione.

机构信息

Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, PR China.

出版信息

Chem Commun (Camb). 2013 Feb 14;49(13):1294-6. doi: 10.1039/c2cc38429a. Epub 2013 Jan 8.

DOI:10.1039/c2cc38429a
PMID:23295243
Abstract

We report a turn-on fluorescent sensor based on nitrothiophenolate boron dipyrromethene (BODIPY) derivatives for the discrimination of cystein (Cys) from homocystein (Hcy) and glutathione (GSH). The sensor was applied for detection of Cys in living cells.

摘要

我们报道了一种基于硝基噻吩硼酸二吡咯甲川(BODIPY)衍生物的荧光传感器,用于区分半胱氨酸(Cys)、同型半胱氨酸(Hcy)和谷胱甘肽(GSH)。该传感器可用于活细胞中 Cys 的检测。

相似文献

1
A turn-on fluorescent sensor for the discrimination of cystein from homocystein and glutathione.一种用于区分半胱氨酸、同型半胱氨酸和谷胱甘肽的荧光传感器。
Chem Commun (Camb). 2013 Feb 14;49(13):1294-6. doi: 10.1039/c2cc38429a. Epub 2013 Jan 8.
2
An aza-BODIPY based near-infrared fluorescent probe for sensitive discrimination of cysteine/homocysteine and glutathione in living cells.一种基于氮杂硼二吡咯的近红外荧光探针,用于灵敏区分活细胞中的半胱氨酸/同型半胱氨酸和谷胱甘肽。
Chem Commun (Camb). 2017 May 4;53(37):5220-5223. doi: 10.1039/c7cc01814b.
3
Development of a small molecule probe capable of discriminating cysteine, homocysteine, and glutathione with three distinct turn-on fluorescent outputs.一种能够通过三种不同的开启式荧光输出区分半胱氨酸、同型半胱氨酸和谷胱甘肽的小分子探针的开发。
Chemistry. 2014 Sep 1;20(36):11471-8. doi: 10.1002/chem.201403450. Epub 2014 Jul 23.
4
BODIPY-based ratiometric fluorescent sensor for highly selective detection of glutathione over cysteine and homocysteine.基于 BODIPY 的比率型荧光传感器,用于高选择性检测谷胱甘肽相对于半胱氨酸和同型半胱氨酸。
J Am Chem Soc. 2012 Nov 21;134(46):18928-31. doi: 10.1021/ja309079f. Epub 2012 Nov 8.
5
Coumarin-malonitrile conjugate as a fluorescence turn-on probe for biothiols and its cellular expression.香豆素-丙二腈缀合物作为生物硫醇的荧光开启探针及其细胞表达。
Chem Commun (Camb). 2011 Feb 14;47(6):1773-5. doi: 10.1039/c0cc04092d. Epub 2010 Dec 2.
6
A series of BODIPY-based probes for the detection of cysteine and homocysteine in living cells.一系列基于 BODIPY 的探针,用于活细胞中半胱氨酸和同型半胱氨酸的检测。
Talanta. 2019 Apr 1;195:281-289. doi: 10.1016/j.talanta.2018.11.066. Epub 2018 Nov 22.
7
A simple excited-state intramolecular proton transfer probe based on a new strategy of thiol-azide reaction for the selective sensing of cysteine and glutathione.一种基于硫醇-叠氮化物反应新策略的简单激发态分子内质子转移探针,用于选择性检测半胱氨酸和谷胱甘肽。
Chem Commun (Camb). 2016 Jan 14;52(4):749-52. doi: 10.1039/c5cc07298k.
8
Broadly Applicable Strategy for the Fluorescence Based Detection and Differentiation of Glutathione and Cysteine/Homocysteine: Demonstration in Vitro and in Vivo.基于荧光检测和区分谷胱甘肽与半胱氨酸/同型半胱氨酸的广泛适用策略:体外和体内验证
Anal Chem. 2016 Apr 5;88(7):3638-46. doi: 10.1021/acs.analchem.5b04333. Epub 2016 Mar 14.
9
A dual-response fluorescent probe for the discrimination of cysteine from glutathione and homocysteine.一种用于从半胱氨酸、谷胱甘肽和高半胱氨酸中区分半胱氨酸的双响应荧光探针。
Spectrochim Acta A Mol Biomol Spectrosc. 2019 Jan 5;206:1-7. doi: 10.1016/j.saa.2018.07.102. Epub 2018 Aug 1.
10
Benzothiazole-Pyimidine-Based BF2 Complex for Selective Detection of Cysteine.用于选择性检测半胱氨酸的基于苯并噻唑-嘧啶的BF2配合物
Chem Asian J. 2016 Jan;11(2):202-6. doi: 10.1002/asia.201501013. Epub 2015 Nov 17.

引用本文的文献

1
Epitaxially grown silicon-based single-atom catalyst for visible-light-driven syngas production.用于可见光驱动合成气生产的外延生长硅基单原子催化剂。
Nat Commun. 2023 Mar 28;14(1):1719. doi: 10.1038/s41467-023-37401-3.
2
Enlightening the Path to Protein Engineering: Chemoselective Turn-On Probes for High-Throughput Screening of Enzymatic Activity.启发蛋白质工程之路:用于高通量筛选酶活性的化学选择性激活探针。
Chem Rev. 2023 Mar 22;123(6):2832-2901. doi: 10.1021/acs.chemrev.2c00304. Epub 2023 Feb 28.
3
A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism.
一种基于双电子转移/分子内电荷转移机制的用于选择性检测半胱氨酸的简单双光子开启荧光探针。
RSC Adv. 2018 Apr 10;8(24):13388-13392. doi: 10.1039/c8ra02138d. eCollection 2018 Apr 9.
4
Novel dual-site fluorescent probe for monitoring cysteine and sulfite in living cells.用于监测活细胞中半胱氨酸和亚硫酸盐的新型双位点荧光探针。
RSC Adv. 2018 Jun 8;8(38):21047-21053. doi: 10.1039/c8ra01683f.
5
A fluorescence and UV/vis absorption dual-signaling probe with aggregation-induced emission characteristics for specific detection of cysteine.一种具有聚集诱导发光特性的荧光和紫外/可见吸收双信号探针,用于特异性检测半胱氨酸。
RSC Adv. 2018 Jul 5;8(43):24346-24354. doi: 10.1039/c8ra03756f. eCollection 2018 Jul 2.
6
Fluorescent Probes for Live Cell Thiol Detection.用于活细胞硫醇检测的荧光探针。
Molecules. 2021 Jun 11;26(12):3575. doi: 10.3390/molecules26123575.
7
Rational design of a "dual lock-and-key" supramolecular photosensitizer based on aromatic nucleophilic substitution for specific and enhanced photodynamic therapy.基于芳香亲核取代反应的“双锁钥”超分子光敏剂的合理设计用于特异性增强光动力治疗
Chem Sci. 2020 Aug 25;11(35):9703-9711. doi: 10.1039/d0sc01122c.
8
Fluorescent probes based on nucleophilic aromatic substitution reactions for reactive sulfur and selenium species: Recent progress, applications, and design strategies.基于亲核芳香取代反应的用于活性硫和硒物种的荧光探针:最新进展、应用及设计策略
Coord Chem Rev. 2021 Jan 15;427:213601. doi: 10.1016/j.ccr.2020.213601. Epub 2020 Oct 2.
9
Recent Emergence of Rhenium(I) Tricarbonyl Complexes as Photosensitisers for Cancer Therapy.最近出现的铼(I)三羰基配合物作为癌症治疗的光敏剂。
Molecules. 2020 Sep 12;25(18):4176. doi: 10.3390/molecules25184176.
10
Exploring cysteine regulation in cancer cell survival with a highly specific "Lock and Key" fluorescent probe for cysteine.利用一种针对半胱氨酸的高度特异性“锁钥”荧光探针探索癌细胞存活中的半胱氨酸调节。
Chem Sci. 2019 Sep 7;10(43):10065-10071. doi: 10.1039/c9sc02618e. eCollection 2019 Nov 21.