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采用近红外光谱技术对易损斑块进行成像,以对动脉粥样硬化进行风险分层。

Imaging of vulnerable plaques using near-infrared spectroscopy for risk stratification of atherosclerosis.

机构信息

Division of Cardiology, The University of Texas Health Science Center, Audie L Murphy VA Hospital, San Antonio, TX, USA.

出版信息

Curr Atheroscler Rep. 2013 Feb;15(2):304. doi: 10.1007/s11883-012-0304-6.

DOI:10.1007/s11883-012-0304-6
PMID:23299644
Abstract

Although the prevalent approach in cardiology is largely "stenosis-centric," it has been long known that most acute coronary events are caused by apparently angiographically nonsignificant stenosis. This has led to a gradual paradigm shift from detection of significant stenosis to detection of lesion instability. A number of imaging modalities have been developed that help in this quest; however, none have been as promising as near-infrared spectroscopy used for detection of coronary plaque characteristics. In this article we discuss the various invasive imaging tools available to the interventional cardiologist, with special emphasis on near-infrared spectroscopy as a key emerging imaging technology.

摘要

尽管心脏病学的主流方法主要是以“狭窄为中心”,但长期以来人们一直知道,大多数急性冠状动脉事件是由明显无显著狭窄的病变引起的。这导致了从检测显著狭窄到检测病变不稳定性的逐渐范式转变。已经开发了许多成像方式来帮助实现这一目标;然而,没有一种方法像近红外光谱那样有前途,用于检测冠状动脉斑块特征。在本文中,我们讨论了介入心脏病学家可用的各种侵入性成像工具,特别强调近红外光谱作为一种关键的新兴成像技术。

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Prediction of progression of coronary artery disease and clinical outcomes using vascular profiling of endothelial shear stress and arterial plaque characteristics: the PREDICTION Study.利用内皮剪切应力和动脉斑块特征的血管分析预测冠状动脉疾病进展和临床结局:PREDICTION 研究。
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NIRS and IVUS for characterization of atherosclerosis in patients undergoing coronary angiography.
近红外光谱和血管内超声在冠状动脉造影患者动脉粥样硬化特征分析中的应用。
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Intercatheter reproducibility of near-infrared spectroscopy for the in vivo detection of coronary lipid core plaques.经导管近红外光谱法在活体检测冠状动脉脂质核心斑块中的可重复性。
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