Hospital Ana Costa, Santos, SP.
Braz J Otorhinolaryngol. 2012 Dec;78(6):77-80. doi: 10.5935/1808-8694.20120037.
There is controversy in the literature regarding the association between papillary thyroid carcinoma (PTC) and Hashimoto's thyroiditis (HT) and as to what would be the etiological relationship between them.
To establish the proportion of cases among patients with TH and CPT, correlating it with histomorphological aspects.
A retrospective study of patients undergoing partial or total thyroidectomy for PTC between 2007 and 2009, a total of 41 cases.
Regarding the association of HT and CPT, we found 11 cases (26.8%), all females, but without statistical significance. The mean age was 44.9 years among the patients with coexistent TH and CPT, whereas it was 49.1 years without that association. The average size of tumors in those without TH was 20.53 mm and for those with TH it was 12.72 mm (p = 0.4). Regarding pathology staging, the ratios between those with and those without TH were kept in T1a, T1b and T3. In T2, there were no cases of coexistence of HT and PTC.
There is a rate of 26.8% of patients with association between TH and CPT, but without differences in relation to tumor size.
关于甲状腺乳头状癌(PTC)与桥本甲状腺炎(HT)之间的关联,以及它们之间存在何种病因关系,文献中存在争议。
确定 HT 和 CPT 患者中的病例比例,并与组织形态学方面相关联。
对 2007 年至 2009 年间行甲状腺部分或全切除术治疗 PTC 的患者进行回顾性研究,共 41 例。
关于 HT 和 CPT 的关联,我们发现了 11 例(26.8%)患者,均为女性,但无统计学意义。伴有 HT 和 CPT 的患者平均年龄为 44.9 岁,而无这种关联的患者平均年龄为 49.1 岁。无 HT 的患者肿瘤平均大小为 20.53mm,而有 HT 的患者肿瘤平均大小为 12.72mm(p=0.4)。在病理分期方面,有和无 HT 的患者之间的比例在 T1a、T1b 和 T3 中保持不变。在 T2 中,没有 HT 和 PTC 共存的病例。
有 26.8%的 HT 患者与 CPT 相关,但与肿瘤大小无差异。