Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Via Balzaretti, Milano, Italy.
Crit Rev Food Sci Nutr. 2013;53(4):403-13. doi: 10.1080/10408398.2012.682123.
Plant food supplements (PFS) receive great acceptance by European consumers. However, quality and efficacy of these products remain a question of concern. The aim of this systematic review is to summarize and critically evaluate the evidence for or against the efficacy of PFS for coping inflammatory conditions by considering epidemiological and human intervention studies. The review, which consists of two parts, considers Olea europea L., Camellia sinensis L., Vitis vinifera L., and Matricaria recutita L., which are herbal material frequently used also as food. The search retrieved 1251 publications. By applying the inclusion/exclusion criteria, the final number of papers was 91. Vitis vinifera L. showed promising results, but other trials should be performed in order to assessing the efficacy. Surprisingly, it was impossible to draw conclusions for the anti-inflammatory effect of Camellia sinensis L. as green tea. No studies were found on the leaves of Olea europea L. whereas more human trials are needed to assess the anti-inflammatory effect of olive oil. Only one study for Matricaria recutita L. was selected. In conclusion, it is advisable to conduct further studies with more homogeneous population and larger number of subjects by avoiding the heterogeneity of the herbal preparations considered.
植物性食品补充剂（PFS）深受欧洲消费者的欢迎。然而，这些产品的质量和功效仍然是人们关注的问题。本系统评价的目的是通过考虑流行病学和人体干预研究，总结和批判性评估 PFS 应对炎症性疾病的功效的证据。该综述分为两部分，考虑了经常用作食品的橄榄（Olea europea L.）、茶叶（Camellia sinensis L.）、葡萄（Vitis vinifera L.）和母菊（Matricaria recutita L.）等植物性材料。检索到 1251 篇出版物。通过应用纳入/排除标准，最终的论文数量为 91 篇。葡萄显示出有希望的结果，但需要进行其他试验以评估其功效。令人惊讶的是，对于绿茶的抗炎作用，无法得出确切结论。关于橄榄叶（Olea europea L.）的研究尚未发现，需要更多的人体试验来评估橄榄油的抗炎作用。仅选择了一项关于母菊（Matricaria recutita L.）的研究。总之，建议通过避免所考虑的草药制剂的异质性，进行具有更同质人群和更大样本量的进一步研究。
