阔叶刺果芹、薰衣草水苏和赤桉植物对阴道毛滴虫体外生长的影响。
Effect of Echinophora platyloba, Stachys lavandulifolia, and Eucalyptus camaldulensis plants on Trichomonas vaginalis growth in vitro.
作者信息
Youse Hossein Ali, Kazemian Afsaneh, Sereshti Manijeh, Rahmanikhoh Elham, Ahmadinia Elham, Rafaian Mahmood, Maghsoodi Reza, Darani Hossein Y
机构信息
Department of Parasitology and Mycology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
Adv Biomed Res. 2012;1:79. doi: 10.4103/2277-9175.102987. Epub 2012 Oct 31.
BACKGROUND
Trichomonas vaginalis is a protozoan parasite which causes vaginitis in women worldwide. Metronidazole with vast side effects is drug of choice for this infection. In search for an alternative drug, in this study the effect of three plants on Trichomonas vaginalis has been investigated in vitro.
MATERIALS AND METHODS
Alcoholic and watery extracts of Echinophora platyloba, Stachys lavandulifolia, and Eucalyptus camaldulensis were prepared. In TYIS culture medium containing alive Trichomonas vaginalis different concentrations of extracts of three plants were added. Following, 24, 48, and 72 h incubation the number of parasite in each test tube was counted.
RESULTS
Eucalyptus camaldulensis showed a strong effect on Trichomonas vaginalis growth. However, no significant effect was observed with Echinophora platyloba or Stachys lavandulifolia extracts.
CONCLUSION
Eucalyptus camaldulensis can be considered as an alternative drug for treatment of infective vaginitis which is caused by bacteria, fungi and parasites.
背景
阴道毛滴虫是一种原生动物寄生虫，可导致全球范围内的女性阴道炎。甲硝唑副作用大，是治疗这种感染的首选药物。为寻找替代药物，本研究在体外研究了三种植物对阴道毛滴虫的作用。
材料与方法
制备了阔叶刺头草、薰衣草水苏和赤桉的乙醇提取物和水提取物。在含有活阴道毛滴虫的TYIS培养基中加入不同浓度的三种植物提取物。随后，在孵育24、48和72小时后，对每个试管中的寄生虫数量进行计数。
结果
赤桉对阴道毛滴虫的生长有强烈作用。然而，阔叶刺头草或薰衣草水苏提取物未观察到显著作用。
结论
赤桉可被视为治疗由细菌、真菌和寄生虫引起的感染性阴道炎的替代药物。
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