Zekai Tahir Women's Health Education and Research Hospital, Ankara, Turkey.
Eur Rev Med Pharmacol Sci. 2013 Jan;17(1):138-40.
To determine vaspin and C-reactive protein (CRP) concentrations in hyperemesis gravidarum (HEG).
Twenty-six women with HEG and 26 control subjects matched for gestational age and body mass index were examined. The levels of vaspin, CRP and lipid profile in all subjects were measured.
The vaspin levels were significantly higher in hyperemetic patients than in the healthy pregnant women (1308.3 ± 116.5 vs. 1145.9 ± 335.1 ng/ml, respectively) (p < 0.05). Women with HEG had significantly higher levels of CRP than the control group. Serum vaspin concentrations inversely correlated with total cholesterol, triglyceride, very low-density lipoprotein-cholesterol and low-density lipoprotein-cholesterol levels.
We found evidence of inflammation in HEG.
测定妊娠剧吐(HEG)患者中脂联素和 C 反应蛋白(CRP)的浓度。
检查了 26 例 HEG 患者和 26 例年龄和体重指数相匹配的健康孕妇。所有受试者的脂联素、CRP 和血脂水平均进行了测量。
与健康孕妇相比,妊娠剧吐患者的脂联素水平显著升高(分别为 1308.3±116.5 与 1145.9±335.1ng/ml)(p<0.05)。妊娠剧吐患者的 CRP 水平显著高于对照组。血清脂联素浓度与总胆固醇、甘油三酯、极低密度脂蛋白胆固醇和低密度脂蛋白胆固醇水平呈负相关。
我们发现妊娠剧吐存在炎症证据。