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新型β-内酰胺类药物对脆弱拟杆菌群成员的比较活性

Comparative activities of newer beta-lactam agents against members of the Bacteroides fragilis group.

作者信息

Cuchural G J, Tally F P, Jacobus N V, Cleary T, Finegold S M, Hill G, Iannini P, O'Keefe J P, Pierson C

机构信息

Department of Medicine, Tufts-New England Medical Center Hospitals, Boston, Massachusetts 02111.

出版信息

Antimicrob Agents Chemother. 1990 Mar;34(3):479-80. doi: 10.1128/AAC.34.3.479.

Abstract

A nationwide susceptibility survey of 557 isolates of the Bacteroides fragilis group was continued in 1986. The most active beta-lactam drugs were imipenem and ticarcillin-clavulanic acid, which had 0.2 and 1.7% resistance, respectively. The rank order of activity of beta-lactam drugs was imipenem, ticarcillin-clavulanic acid, cefoxitin, piperacillin, moxalactam, ceftizoxime, cefotetan, cefotaxime, cefoperazone, and ceftazadime.

摘要

1986年继续对557株脆弱拟杆菌属菌株进行了一项全国性药敏调查。活性最强的β-内酰胺类药物是亚胺培南和替卡西林-克拉维酸,其耐药率分别为0.2%和1.7%。β-内酰胺类药物的活性排序为亚胺培南、替卡西林-克拉维酸、头孢西丁、哌拉西林、拉氧头孢、头孢唑肟、头孢替坦、头孢噻肟、头孢哌酮和头孢他啶。

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