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1
Activity of newer beta-lactam agents against clinical isolates of Bacteroides fragilis and other Bacteroides species.新型β-内酰胺类药物对脆弱拟杆菌及其他拟杆菌属临床分离株的活性。
Antimicrob Agents Chemother. 1987 Dec;31(12):2002-4. doi: 10.1128/AAC.31.12.2002.
2
Comparative activities of newer beta-lactam agents against members of the Bacteroides fragilis group.新型β-内酰胺类药物对脆弱拟杆菌群成员的比较活性
Antimicrob Agents Chemother. 1990 Mar;34(3):479-80. doi: 10.1128/AAC.34.3.479.
3
Susceptibility of 114 isolates of the Bacteroides fragilis group to imipenem and eight other antimicrobial agents.114株脆弱拟杆菌属菌株对亚胺培南及其他8种抗菌药物的敏感性
Pathology. 1988 Jul;20(3):260-3. doi: 10.3109/00313028809059504.
4
Newer beta-lactam agents and the Bacteroides fragilis group.新型β-内酰胺类药物与脆弱拟杆菌群
Pharmacotherapy. 1991;11(2 ( Pt 2)):51S-55S.
5
Survey of Bacteroides fragilis group susceptibility patterns in Canada.加拿大脆弱拟杆菌群药敏模式调查。
Antimicrob Agents Chemother. 1992 Feb;36(2):343-7. doi: 10.1128/AAC.36.2.343.
6
In-vitro activity of amoxycillin and ticarcillin in combination with clavulanic acid compared with that of new beta-lactam agents against species of the Bacteroides fragilis group.阿莫西林和替卡西林与克拉维酸联合使用的体外活性与新型β-内酰胺类药物针对脆弱拟杆菌群各菌种的活性比较。
J Antimicrob Chemother. 1986 May;17(5):593-603. doi: 10.1093/jac/17.5.593.
7
Annual incidence, epidemiology, and comparative in vitro susceptibilities to cefoxitin, cefotetan, cefmetazole, and ceftizoxime of recent community-acquired isolates of the Bacteroides fragilis group.脆弱拟杆菌群近期社区获得性分离株的年发病率、流行病学以及对头孢西丁、头孢替坦、头孢美唑和头孢唑肟的体外敏感性比较
J Clin Microbiol. 1988 Nov;26(11):2361-6. doi: 10.1128/jcm.26.11.2361-2366.1988.
8
Cross-resistance to beta-lactam-beta-lactamase inhibitor combinations and clindamycin among cefoxitin-resistant and cefoxitin-susceptible strains of the Bacteroides fragilis group.脆弱拟杆菌群中对头孢西丁耐药和敏感菌株对β-内酰胺-β-内酰胺酶抑制剂组合及克林霉素的交叉耐药性
Diagn Microbiol Infect Dis. 1993 Oct;17(3):251-6. doi: 10.1016/0732-8893(93)90107-i.
9
The antimicrobial susceptibility patterns of the Bacteroides fragilis group in the United States, 1987.1987年美国脆弱拟杆菌群的抗菌药敏模式。
J Antimicrob Chemother. 1990 Jun;25(6):1011-9. doi: 10.1093/jac/25.6.1011.
10
Beta-lactamase production and susceptibilities to amoxicillin, amoxicillin-clavulanate, ticarcillin, ticarcillin-clavulanate, cefoxitin, imipenem, and metronidazole of 320 non-Bacteroides fragilis Bacteroides isolates and 129 fusobacteria from 28 U.S. centers.来自美国28个中心的320株非脆弱拟杆菌属拟杆菌分离株和129株梭杆菌属细菌的β-内酰胺酶产生情况以及对阿莫西林、阿莫西林-克拉维酸、替卡西林、替卡西林-克拉维酸、头孢西丁、亚胺培南和甲硝唑的敏感性。
Antimicrob Agents Chemother. 1990 Aug;34(8):1546-50. doi: 10.1128/AAC.34.8.1546.

引用本文的文献

1
Longitudinal study of susceptibilities of species of the Bacteroides fragilis group to five antimicrobial agents in three medical centers.在三个医学中心对脆弱拟杆菌群的物种对五种抗菌药物的敏感性进行的纵向研究。
Antimicrob Agents Chemother. 1994 Oct;38(10):2276-9. doi: 10.1128/AAC.38.10.2276.
2
Annual incidence, epidemiology, and comparative in vitro susceptibilities to cefoxitin, cefotetan, cefmetazole, and ceftizoxime of recent community-acquired isolates of the Bacteroides fragilis group.脆弱拟杆菌群近期社区获得性分离株的年发病率、流行病学以及对头孢西丁、头孢替坦、头孢美唑和头孢唑肟的体外敏感性比较
J Clin Microbiol. 1988 Nov;26(11):2361-6. doi: 10.1128/jcm.26.11.2361-2366.1988.
3
Comparative in vitro antimicrobial susceptibilities of a special panel of 74 Bacteroides fragilis group isolates in Wilkins-Chalgren agar with and without sheep blood.74株脆弱拟杆菌群菌株的特殊菌组在含和不含羊血的威尔金斯-查尔格伦琼脂中的体外抗菌敏感性比较
Antimicrob Agents Chemother. 1989 Mar;33(3):394-5. doi: 10.1128/AAC.33.3.394.
4
Ceftizoxime: a third-generation cephalosporin active against anaerobic bacteria. Committee on Antimicrobial Agents, Canadian Infectious Disease Society.头孢唑肟：一种对厌氧菌有效的第三代头孢菌素。抗菌药物委员会，加拿大传染病协会。
CMAJ. 1990 Jun 1;142(11):1209-12.
5
Spiral gradient endpoint method compared to standard agar dilution for susceptibility testing of anaerobic gram-negative bacilli.螺旋梯度终点法与标准琼脂稀释法用于厌氧革兰氏阴性杆菌药敏试验的比较。
J Clin Microbiol. 1991 May;29(5):975-9. doi: 10.1128/jcm.29.5.975-979.1991.
6
Effect of beta-lactamase inhibitors on the activities of various beta-lactam agents against anaerobic bacteria.β-内酰胺酶抑制剂对各种β-内酰胺类药物抗厌氧菌活性的影响。
Antimicrob Agents Chemother. 1991 Jun;35(6):1219-24. doi: 10.1128/AAC.35.6.1219.
7
In vitro susceptibilities of the Bacteroides fragilis group to 14 antimicrobial agents in Korea.韩国脆弱拟杆菌群对14种抗菌药物的体外敏感性
Antimicrob Agents Chemother. 1992 Jan;36(1):195-7. doi: 10.1128/AAC.36.1.195.

本文引用的文献

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A randomized comparison of cefoxitin with or without amikacin and clindamycin plus amikacin in surgical sepsis.头孢西丁联合或不联合阿米卡星与克林霉素加阿米卡星治疗外科脓毒症的随机对照研究
Ann Surg. 1981 Mar;193(3):318-23. doi: 10.1097/00000658-198103000-00011.
2
Antimicrobial susceptibilities of 1,292 isolates of the Bacteroides fragilis group in the United States: comparison of 1981 with 1982.美国1292株脆弱拟杆菌属细菌的药敏情况：1981年与1982年的比较
Antimicrob Agents Chemother. 1984 Aug;26(2):145-8. doi: 10.1128/AAC.26.2.145.
3
Risk of infection after penetrating abdominal trauma.穿透性腹部创伤后的感染风险。
N Engl J Med. 1984 Oct 25;311(17):1065-70. doi: 10.1056/NEJM198410253111701.
4
Prospective, randomized, comparative trials in the therapy for intraabdominal and female genital tract infections.
Rev Infect Dis. 1984 Mar-Apr;6 Suppl 1:S283-92. doi: 10.1093/clinids/6.supplement_1.s283.
5
Antimicrobial activity of desacetylcefotaxime alone and in combination with cefotaxime: evidence of synergy.去乙酰头孢噻肟单独及与头孢噻肟联合应用的抗菌活性：协同作用证据
Rev Infect Dis. 1982 Sep-Oct;4 Suppl:S366-73. doi: 10.1093/clinids/4.supplement_2.s366.
6
Clinical pharmacokinetics of cefotaxime in patients with normal and reduced renal function.头孢噻肟在肾功能正常和减退患者中的临床药代动力学
Rev Infect Dis. 1982 Sep-Oct;4 Suppl:S333-45. doi: 10.1093/clinids/4.supplement_2.s333.
7
Nationwide study of the susceptibility of the Bacteroides fragilis group in the United States.美国全国范围内脆弱拟杆菌群药敏性研究。
Antimicrob Agents Chemother. 1985 Nov;28(5):675-7. doi: 10.1128/AAC.28.5.675.
8
Comparative clinical evaluation of ceftizoxime with clindamycin and gentamicin and cefoxitin in the treatment of postcesarean endomyometritis.头孢唑肟与克林霉素、庆大霉素及头孢西丁治疗剖宫产术后子宫内膜炎的临床对比评估
Surg Gynecol Obstet. 1985 Dec;161(6):518-22.
9
Randomized prospective study comparing moxalactam and cefoxitin with or without tobramycin for the treatment of serious surgical infections.比较羟羧氧酰胺菌素和头孢西丁联合或不联合妥布霉素治疗严重外科感染的随机前瞻性研究。
Antimicrob Agents Chemother. 1986 Feb;29(2):244-9. doi: 10.1128/AAC.29.2.244.
10
Activity of cefazolin and two beta-lactamase inhibitors, clavulanic acid and sulbactam, against Bacteroides fragilis.头孢唑林及两种β-内酰胺酶抑制剂（克拉维酸和舒巴坦）对脆弱拟杆菌的活性。
Antimicrob Agents Chemother. 1987 Feb;31(2):321-2. doi: 10.1128/AAC.31.2.321.

新型β-内酰胺类药物对脆弱拟杆菌及其他拟杆菌属临床分离株的活性。

Activity of newer beta-lactam agents against clinical isolates of Bacteroides fragilis and other Bacteroides species.

作者信息

O'Keefe J P, Venezio F R, DiVincenzo C A, Shatzer K L

机构信息

Infectious Disease Research Laboratory, Loyola University Medical Center, Maywood, Illinois 60153.

出版信息

Antimicrob Agents Chemother. 1987 Dec;31(12):2002-4. doi: 10.1128/AAC.31.12.2002.

DOI:10.1128/AAC.31.12.2002
PMID:3439807
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC175843/
Abstract

The in vitro activities of beta-lactam antibiotics against Bacteroides fragilis and B. fragilis group isolates are presented. Clinical isolates from 1986 were compared with strains from 1979 to 1982. Imipenem, ticarcillin-clavulanic acid, and ceftizoxime were the most active agents. Cefotetan was equivalent to cefoxitin against B. fragilis but less active against B. fragilis group isolates. Enhancement of cefotaxime by its desacetyl metabolite was minimal.

摘要

本文介绍了β-内酰胺类抗生素对脆弱拟杆菌及脆弱拟杆菌群分离株的体外活性。将1986年的临床分离株与1979年至1982年的菌株进行了比较。亚胺培南、替卡西林-克拉维酸和头孢唑肟是活性最强的药物。头孢替坦对脆弱拟杆菌的活性与头孢西丁相当，但对脆弱拟杆菌群分离株的活性较低。头孢噻肟的去乙酰代谢产物对其活性的增强作用极小。