Scarfì M R, Romanò M, Di Pietro R, Zeni O, Doria A, Gallerano G P, Giovenale E, Messina G, Lai A, Campurra G, Coniglio D, D'Arienzo M
CNR-IREA, Via Diocleziano 328, 80124 Napoli (I).
J Biol Phys. 2003 Jun;29(2-3):171-6. doi: 10.1023/A:1024440708943.
The aim of the present study is toinvestigate the genotoxic effect of THzradiation in human peripheral bloodlymphocytes following 20 minutes exposureto 1 mW average power Free Electron Laserradiation in the frequency range 120-140GHz. For this purpose 9 healthy donors wereemployed and cytokinesis block techniquewas applied to study micronucleusfrequency and cell proliferation. Theresults obtained indicate that all theelectromagnetic conditions adopted so far do not alter the investigated parameters,suggesting absence of direct chromosomaldamage and alteration of cell cyclekinetics (two tailed paired Student's test:p> 0.05 in all cases).
本研究的目的是调查在120 - 140GHz频率范围内，平均功率为1mW的自由电子激光辐射照射20分钟后，太赫兹辐射对人外周血淋巴细胞的遗传毒性作用。为此，招募了9名健康供者，并应用胞质分裂阻滞技术来研究微核频率和细胞增殖。所获得的结果表明，迄今为止采用的所有电磁条件均未改变所研究的参数，这表明不存在直接的染色体损伤和细胞周期动力学改变（双尾配对学生检验：所有情况下p>0.05）。
