Coster H G L
Department of Biophysics, School of Physics and the Centre for Membrane Science and Technology, University of New South Wales, Sydney, 2051 Australia.
J Biol Phys. 2003 Dec;29(4):363-99. doi: 10.1023/A:1027362704125.
An overview is given of the fundamental physics underlying the self-assembly, molecular organisation and electrical properties of the membranes that envelop living cells. These ultra thin (∼ 6 nm) membranes act as a diffusion barrier between the cell interior (cytoplasm) and the external medium. They consist basically of a bi-molecular film of lipid molecules in which are embedded functional proteins that perform a variety of functions, including energy transduction, signalling, transport of ions (and othermolecules), etc. Some examples are also presented of the fascinating and socially and commercially important applications of membrane biophysics.
本文概述了包裹活细胞的膜的自组装、分子组织和电学性质背后的基础物理学。这些超薄（约6纳米）的膜充当细胞内部（细胞质）与外部介质之间的扩散屏障。它们基本上由脂质分子的双分子膜组成，其中嵌入了执行各种功能的功能蛋白，包括能量转换、信号传导、离子（和其他分子）运输等。还列举了一些膜生物物理学在迷人且具有社会和商业重要性的应用方面的例子。
