Budhiraja Shilpa, Bhavsar Neeta, Kumar Santosh, Desai Khushboo, Duseja Sareen
Department of Periodontology, Karnavati School of Dentistry, Gandhinagar, India.
J Periodontal Implant Sci. 2012 Dec;42(6):237-42. doi: 10.5051/jpis.2012.42.6.237. Epub 2012 Dec 31.
The aim of this study was to clinically and radiographically evaluate and compare treatment of intrabony defects with the use of decalcified freeze-dried bone allograft in combination with a calcium sulphate barrier to collagen membrane.
Twelve patients having chronic periodontal disease aged 20 to 50 years and with a probing depth >6 mm were selected. Classification of patient defects into experimental and control groups was made randomly. In the test group, a calcium sulphate barrier membrane, and in control group, a collagen membrane, was used in conjunction with decalcified freeze-dried bone graft in both sides. Ancillary parameters as well as soft tissue parameters along with radiographs were taken at baseline and after 6 months of surgery. Parameters assessed were plaque index, modified gingival index, probing depth, relative attachment level, and location of the gingival margin. A Student's t-test was done for intragroup and a paired t-test for intergroup analysis.
Intragroup analysis revealed statistically significant improvement in all the ancillary parameters and soft tissue parameters with no statistically significant difference in intergroup analysis.
The study concluded that a calcium sulphate barrier was comparable to collagen membrane in achieving clinical benefits and hence it can be used as an economical alternative to collagen membrane.
本研究旨在临床和影像学方面评估并比较使用脱钙冻干骨移植联合硫酸钙屏障与胶原膜治疗骨内缺损的效果。
选取12例年龄在20至50岁之间、探诊深度>6mm的慢性牙周病患者。将患者缺损随机分为实验组和对照组。实验组在两侧使用硫酸钙屏障膜，对照组在两侧使用胶原膜，并联合脱钙冻干骨移植。在基线期和手术后6个月记录辅助参数、软组织参数以及影像学资料。评估的参数包括菌斑指数、改良牙龈指数、探诊深度、相对附着水平和牙龈边缘位置。组内分析采用学生t检验，组间分析采用配对t检验。
组内分析显示所有辅助参数和软组织参数均有统计学意义上的显著改善，组间分析无统计学意义上的显著差异。
该研究得出结论，硫酸钙屏障在实现临床益处方面与胶原膜相当，因此可作为胶原膜的经济替代物使用。
