Department of Medicine, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Norfolk Place, London, W2 1PG, UK.
Infection. 2013 Jun;41(3):731-4. doi: 10.1007/s15010-013-0409-z. Epub 2013 Feb 3.
We report the first published case of integrase inhibitor resistance in the central nervous system compartment in the absence of evidence of integrase inhibitor resistance in the plasma of a patient without human immunodeficiency virus (HIV)-encephalitis in the context of other HIV-associated central nervous system infections.
我们报道了首例在无 HIV 脑炎的患者的血浆中未发现整合酶抑制剂耐药证据的情况下,中枢神经系统中出现整合酶抑制剂耐药的首例病例,该患者还合并有其他与 HIV 相关的中枢神经系统感染。