Gonda R, Tomoda M, Shimizu N, Kanari M
Kyoritsu College of Pharmacy, Tokyo, Japan.
Chem Pharm Bull (Tokyo). 1990 Feb;38(2):482-6. doi: 10.1248/cpb.38.482.
Three polysaccharides, named ukonan A, ukonan B and ukonan C, were isolated from the rhizomes of Curcuma longa L. They were homogeneous on electrophoresis and gel chromatography, and showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test. They are composed of L-arabinose: D-xylose: D-galactose: D-glucose: L-rhamnose: D-galacturonic acid in the molar ratios of 12:4:12:1:4:10 (ukonan A), 12:4:12:1:2:4 (ukonan B) and 8:3:6:14:2:3 (ukonan C), in addition to small amounts of peptide moiety. Methylation analysis, carbon-13 nuclear magnetic resonance and periodate oxidation studies indicated the structural features of ukonan B, the major one in terms of the activity. It has acidic arabino-galactan type structural units.
从姜黄的根茎中分离出三种多糖，分别命名为ukonan A、ukonan B和ukonan C。它们在电泳和凝胶色谱上均表现为均一性，并且在碳清除试验中显示出显著的网状内皮系统增强活性。它们由L-阿拉伯糖、D-木糖、D-半乳糖、D-葡萄糖、L-鼠李糖、D-半乳糖醛酸以摩尔比12:4:12:1:4:10（ukonan A）、12:4:12:1:2:4（ukonan B）和8:3:6:14:2:3（ukonan C）组成，此外还含有少量肽部分。甲基化分析、碳-13核磁共振和高碘酸盐氧化研究表明了ukonan B的结构特征，ukonan B是活性方面的主要成分。它具有酸性阿拉伯半乳聚糖型结构单元。
