糖尿病患者的低血糖无感知和低血糖反应缺陷：机制和新兴治疗方法。
Defective counterregulation and hypoglycemia unawareness in diabetes: mechanisms and emerging treatments.
机构信息
Division of Endocrinology, Metabolism & Lipid Research, Department of Medicine, Washington University, St Louis, MO 63110, USA.
出版信息
Endocrinol Metab Clin North Am. 2013 Mar;42(1):15-38. doi: 10.1016/j.ecl.2012.11.005. Epub 2012 Dec 12.
Abstract
For people with diabetes, hypoglycemia remains the limiting factor in achieving glycemic control. This article reviews recent advances in how the brain senses and responds to hypoglycemia. Novel mechanisms by which individuals with insulin-treated diabetes develop hypoglycemia unawareness and impaired counterregulatory responses are outlined. Prevention strategies for reducing the incidence of hypoglycemia are discussed.
摘要
对于糖尿病患者来说，低血糖仍然是控制血糖的限制因素。本文综述了大脑感知和应对低血糖的最新进展。概述了接受胰岛素治疗的糖尿病患者出现低血糖意识障碍和受损的代偿反应的新机制。还讨论了降低低血糖发生率的预防策略。
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