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产褥期妇女在三级转诊医院治疗后的弓形体病血清流行率。

Seroprevalence of Toxoplasmosis in Puerperal Women Treated at a Tertiary Referral Hospital.

机构信息

Faculdade de Medicina, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.

出版信息

Rev Bras Ginecol Obstet. 2023 Feb;45(2):59-64. doi: 10.1055/s-0043-1764495. Epub 2023 Mar 28.

Abstract

OBJECTIVE

To evaluate the seroprevalence of toxoplasmosis among puerperal women cared for at a tertiary university hospital and the level of understanding of these puerperal women about toxoplasmosis, vertical transmission, and its prophylaxis.

METHODS

For this cross-sectional study, we evaluated 225 patients using presential interviews, prenatal documentation, and electronic medical records. Data were stored using Research Electronic Data Capture (REDCap) software. Prevalence rates were estimated by the presence of reactive IgG antibodies against . Data analysis was performed using the chi-square test and calculation of the odds ratio (OR). Seroreactivity to and exposure variables (age, educational level, and parity) were analyzed using a confidence interval (95%CI) and a significance level of 5% (p < 0.05).

RESULTS

The seropositivity rate for was 40%. There was no association between seroprevalence and age. Primiparity was a protective factor against seropositivity and low education was a risk factor.

CONCLUSION

Knowledge of infection and its transmission forms was significantly limited, presenting a risk for acute maternal toxoplasmosis and vertical transmission of this protozoan. Increasing the education level regarding the risk of toxoplasmosis during pregnancy could reduce the rates of infection and vertical transmission of this parasite.

摘要

目的

评估在一家三级大学医院接受治疗的产后妇女的弓形虫病血清流行率,以及这些产后妇女对弓形虫病、垂直传播及其预防的理解程度。

方法

在这项横断面研究中,我们通过面对面访谈、产前记录和电子病历评估了 225 名患者。使用 Research Electronic Data Capture (REDCap) 软件存储数据。通过存在针对. 的反应性 IgG 抗体来估计流行率。使用卡方检验和计算比值比(OR)进行数据分析。使用置信区间(95%CI)和 5%的显著性水平(p<0.05)分析血清反应性和暴露变量(年龄、教育水平和产次)。

结果

弓形虫病的血清阳性率为 40%。血清流行率与年龄之间没有关联。初产是血清阳性的保护因素,而低教育是危险因素。

结论

对 感染及其传播形式的认识明显有限,这对急性母体弓形虫病和这种原生动物的垂直传播构成了风险。在妊娠期间提高有关弓形虫病风险的教育水平可以降低这种寄生虫的感染和垂直传播率。

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