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注意缺陷多动障碍家族风险学龄前儿童的反应抑制:一项行为和电生理停止信号研究。

Response inhibition in preschoolers at familial risk for attention deficit hyperactivity disorder: a behavioral and electrophysiological stop-signal study.

机构信息

Department of Psychology and Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev.

出版信息

Child Dev. 2013 Sep-Oct;84(5):1616-32. doi: 10.1111/cdev.12072. Epub 2013 Feb 28.

DOI:10.1111/cdev.12072
PMID:23448499
Abstract

Children participating in the Ben-Gurion Infant Development Study were assessed with a dynamic-tracking version of the stop-signal task at the age of 5 years. The sample consisted of 60 males. Stop-signal reaction time (SSRT) was correlated with concurrent ratings of the child's attention deficit hyperactivity disorder (ADHD) symptoms. Paternal symptoms measured in the child's early infancy predicted the child's performance in the stop-signal task: Paternal inattentiveness predicted SSRT, whereas hyperactivity predicted error proportion. Maternal symptoms were not correlated with the performance of the child in the task. A subsample of children, who were tested while electrophysiological brain activity was measured, showed that having higher ADHD symptomatology, especially hyperactivity, correlated with less activity in the brain areas that are usually recruited by children for successful inhibition.

摘要

参与本古里安婴儿发育研究的儿童在 5 岁时接受了一种动态追踪版的停止信号任务评估。样本由 60 名男性组成。停止信号反应时间(SSRT)与同时对儿童注意力缺陷多动障碍(ADHD)症状的评定相关。在儿童婴儿早期测量的父亲症状预测了儿童在停止信号任务中的表现:父亲的注意力不集中预测了 SSRT,而多动则预测了错误比例。母亲的症状与儿童在任务中的表现无关。对一部分接受了脑电图脑活动测量的儿童进行的测试表明,ADHD 症状更严重,尤其是多动,与大脑区域的活动减少有关,而这些大脑区域通常是儿童成功抑制所需要的。

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