扎伊尔金沙萨女性性工作者中的人类嗜T细胞病毒I型（HTLV-I）

Human T cell lymphotropic virus type I (HTLV-I) among female prostitutes in Kinshasa, Zaire.

作者信息

Wiktor S Z, Piot P, Mann J M, Nzilambi N, Francis H, Vercauteren G, Blattner W A, Quinn T C

机构信息

Viral Epidemiology Section, National Cancer Institute, Bethesda, MD 20892.

出版信息

J Infect Dis. 1990 Jun;161(6):1073-7. doi: 10.1093/infdis/161.6.1073.

DOI:10.1093/infdis/161.6.1073

PMID:2345292

Abstract

Three hundred seventy-seven prostitutes from Kinshasa, Zaire, were enrolled in a study to determine associated risk factors for human immunodeficiency virus type 1 (HIV-1) and human T cell lymphotropic virus type I (HTLV-I) infection. Twelve samples (3.2%) were seropositive for HTLV-I; results for HIV-1 (101 [26.8%]) are reported elsewhere. HTLV-I prevalence increased with age, and seven of the seropositive women originated from the Equateur region, a remote area in northwestern Zaire. The prevalence among women from Equateur (7.2%) was higher than that of women from all other regions (1.8%, P = .02). Presence of HTLV-I antibodies was not associated with frequency or type of sex practice. In a subsequent study, 350 serum samples were obtained from a variety of subjects in the Equateur region in 1986. Nineteen (5.4%) showed antibodies to HTLV-I. These data and a recent report of a cluster of patients with tropical spastic paraparesis from this region suggest that HTLV-I is endemic in the Equateur region of Zaire.

摘要

来自扎伊尔金沙萨的377名妓女参与了一项研究，以确定1型人类免疫缺陷病毒（HIV-1）和I型人类嗜T细胞病毒（HTLV-I）感染的相关危险因素。12份样本（3.2%）HTLV-I血清学呈阳性；HIV-1的检测结果（101份[26.8%]）在其他地方报告。HTLV-I感染率随年龄增长而升高，血清学阳性的7名女性来自赤道省，该省位于扎伊尔西北部，是一个偏远地区。赤道省女性的感染率（7.2%）高于所有其他地区的女性（1.8%，P = 0.02）。HTLV-I抗体的存在与性行为的频率或类型无关。在随后的一项研究中，1986年从赤道省的各类人群中采集了350份血清样本。19份（5.4%）样本显示有HTLV-I抗体。这些数据以及最近一份关于该地区一群热带痉挛性截瘫患者的报告表明，HTLV-I在扎伊尔赤道省呈地方性流行。