Department of Pharmaceutics and Pharmaceutical Technology, SSR College of Pharmacy, Sayli-Silvassa Road, U.T. of Dadra and Nagar Haveli, Sayli, Silvassa 396 230, India.
Carbohydr Polym. 2013 Feb 15;92(2):1685-99. doi: 10.1016/j.carbpol.2012.11.021. Epub 2012 Nov 15.
A large number of plant based pharmaceutical excipients are available today. Gums and mucilages are the most commonly available plant ingredients with a wide range of applications in pharmaceutical and cosmetic industries. They are being used due to their abundance in nature, safety and economy. They have been extensively explored as pharmaceutical excipients. They are biocompatible, cheap and easily available. Natural materials have advantages over synthetic ones since they are chemically inert, nontoxic, less expensive, biodegradable and widely available. They can also be modified in different ways to obtain tailor-made materials for drug delivery systems and thus can compete with the available synthetic excipients. Recent trend toward the use of plant based and natural products demands the replacement of synthetic additives with natural ones. In this review, we describe the pharmaceutical applications of various natural gums, mucilages and their modified forms for the development of various drug delivery systems.
如今，有大量基于植物的药物辅料。胶和胶浆是最常见的植物成分，在制药和化妆品行业有广泛的应用。由于它们在自然界中丰富、安全和经济，因此被广泛应用。它们已被广泛探索作为药物辅料。它们具有生物相容性、廉价且易于获得。天然材料比合成材料具有优势，因为它们化学惰性、无毒、更便宜、可生物降解且广泛可用。它们还可以通过不同的方式进行修饰，以获得用于药物传递系统的定制材料，从而与现有的合成辅料竞争。最近，人们趋向于使用基于植物的和天然产品，这就要求用天然添加剂替代合成添加剂。在这篇综述中，我们描述了各种天然胶、胶浆及其改性形式在各种药物传递系统开发中的药物应用。
