Dermatological Sciences, Institute of Inflammation and Repair, University of Manchester, Manchester, UK.
Photodermatol Photoimmunol Photomed. 2013 Apr;29(2):57-64. doi: 10.1111/phpp.12021.
Exposure to ultraviolet radiation can lead to suppression of many adaptive immune responses, both to antigens encountered within a short period of the irradiation (primary) and to antigens previously encountered (memory). The pathways involved are complex and not completely elucidated. This brief review summarizes the information available currently regarding the multiple steps involved, with the aim of providing a general overview of the main aspects of photoimmunosuppression and its clinical consequences.
紫外线辐射暴露可导致许多适应性免疫应答受到抑制，这些应答既针对照射后短期内遇到的抗原（原发性），也针对先前遇到过的抗原（记忆性）。涉及的途径复杂，尚未完全阐明。这篇简短的综述总结了目前有关多个涉及步骤的信息，旨在提供对光免疫抑制及其临床后果的主要方面的概述。
