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不同的高血压流行定义影响:高血压的临床流行病学和实现“健康人”目标。

Different definitions of prevalent hypertension impact: the clinical epidemiology of hypertension and attainment of Healthy People goals.

机构信息

General Medicine Division, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.

出版信息

J Clin Hypertens (Greenwich). 2013 Mar;15(3):154-61. doi: 10.1111/jch.12057. Epub 2012 Dec 26.

Abstract

Prevalent hypertension in National Health and Nutrition Examination Surveys (NHANES) is traditionally defined as blood pressure (BP) ≥140 mm Hg systolic and/or ≥90 diastolic and/or currently taking antihypertensive medications. When estimating prevalent hypertension, American Heart Association (AHA) statistical updates include the traditional definition of hypertension (tHTN) and untreated individuals with nonhypertensive BP told twice that they were hypertensive (nontraditional [ntHTN]). The characteristics of ntHTN and their impact on the clinical epidemiology of hypertension and Healthy People prevention and control goals are undefined. NHANES 1999-2002, 2003-2006, and 2007-2010 were analyzed. The ntHTN group was younger and had less diabetes and lower BP than the tHTN group but higher BP than the normotensive group. When classifying ntHTN as hypertensive, prevalent hypertension increased approximately 3% and control 5% to 6% across NHANES periods. In 2007-2010, the Healthy People 2010 goal of controlling BP in 50% of all hypertensive patientss was attained when ntHTN was classified as hypertension (56.5% [95% confidence interval (CI), 54.2-58.7]) and nonhypertension (51.8% [95% CI, 49.6-53.9]). When including ntHTN in prevalent hypertension estimates, the Healthy People 2020 goal of controlling BP in 60% of hypertensive patients becomes more attainable, whereas reducing prevalent hypertension to 26.9% (31.8% [95% CI, 30.5-33.1]) vs 28.7% [95% CI, 27.5-30.0]) becomes more challenging.

摘要

传统上,美国国家健康和营养检查调查(NHANES)中的普遍高血压定义为收缩压(BP)≥140mmHg 和/或舒张压≥90mmHg 和/或目前正在服用抗高血压药物。在估计普遍高血压时,美国心脏协会(AHA)统计更新包括高血压的传统定义(tHTN)和未经治疗的非高血压 BP 两次告知为高血压的个体(非传统[ntHTN])。ntHTN 的特征及其对高血压临床流行病学和“健康人民”预防和控制目标的影响尚未确定。分析了 NHANES 1999-2002、2003-2006 和 2007-2010 年的数据。ntHTN 组比 tHTN 组年轻,糖尿病和血压较低,但比正常血压组高。当将 ntHTN 归类为高血压时,高血压的流行率增加了约 3%,控制率增加了 5%至 6%。在 2007-2010 年,当将 ntHTN 归类为高血压(56.5%[95%置信区间(CI),54.2-58.7])和非高血压(51.8%[95% CI,49.6-53.9])时,实现了“健康人民 2010 年控制所有高血压患者 50%血压”的目标。当将 ntHTN 纳入流行高血压估计值时,“健康人民 2020 年控制 60%高血压患者血压”的目标变得更易于实现,而将流行高血压降低到 26.9%(31.8%[95% CI,30.5-33.1])变得更具挑战性。

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