Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands,
Neth Heart J. 2013 Apr;21(4):166-72. doi: 10.1007/s12471-013-0383-1.
Cardiopulmonary interactions induced by mechanical ventilation are complex and only partly understood. Applied tidal volumes and/or airway pressures largely mediate changes in right ventricular preload and afterload. Effects on left ventricular function are mostly secondary to changes in right ventricular loading conditions. It is imperative to dissect the several causes of haemodynamic compromise during mechanical ventilation as undiagnosed ventricular dysfunction may contribute to morbidity and mortality.
机械通气引起的心肺相互作用非常复杂，目前只是部分了解。潮气量和/或气道压力的应用在很大程度上调节右心室前负荷和后负荷的变化。对左心室功能的影响主要继发于右心室负荷条件的变化。在机械通气期间，必须剖析引起血流动力学障碍的几个原因，因为未诊断的心室功能障碍可能导致发病率和死亡率增加。
