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液体反应性的基本概念。

Basic concepts of fluid responsiveness.

机构信息

Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands,

出版信息

Neth Heart J. 2013 Dec;21(12):530-6. doi: 10.1007/s12471-013-0487-7.

DOI:10.1007/s12471-013-0487-7
PMID:24170232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3833913/
Abstract

Predicting fluid responsiveness, the response of stroke volume to fluid loading, is a relatively novel concept that aims to optimise circulation, and as such organ perfusion, while avoiding futile and potentially deleterious fluid administrations in critically ill patients. Dynamic parameters have shown to be superior in predicting the response to fluid loading compared with static cardiac filling pressures. However, in routine clinical practice the conditions necessary for dynamic parameters to predict fluid responsiveness are frequently not met. Passive leg raising as a means to alter biventricular preload in combination with subsequent measurement of the change in stroke volume can provide a fast and accurate way to guide fluid management in a broad population of critically ill patients.

摘要

预测液体反应性,即血容量对液体负荷的反应性,是一个相对较新的概念,旨在优化循环,从而优化器官灌注,同时避免在危重病患者中进行无效和潜在有害的液体治疗。与静态心脏充盈压相比,动态参数在预测液体反应性方面显示出优越性。然而,在常规临床实践中,动态参数预测液体反应性的必要条件往往得不到满足。被动抬腿作为一种改变双心室前负荷的方法,结合随后测量的每搏量变化,可以为广泛的危重病患者提供一种快速、准确的指导液体管理的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f34/3833913/3c5e9d9bdeaa/12471_2013_487_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f34/3833913/2eecedd554e4/12471_2013_487_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f34/3833913/c91219cdd3f2/12471_2013_487_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f34/3833913/9f558f3fa696/12471_2013_487_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f34/3833913/3c5e9d9bdeaa/12471_2013_487_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f34/3833913/2eecedd554e4/12471_2013_487_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f34/3833913/c91219cdd3f2/12471_2013_487_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f34/3833913/9f558f3fa696/12471_2013_487_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f34/3833913/3c5e9d9bdeaa/12471_2013_487_Fig4_HTML.jpg

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