Magid David J, Olson Kari L, Billups Sarah J, Wagner Nicole M, Lyons Ella E, Kroner Beverly A
Kaiser Permanente Colorado, 10065 E Harvard Ave, Denver, CO 80231, USA.
Circ Cardiovasc Qual Outcomes. 2013 Mar 1;6(2):157-63. doi: 10.1161/CIRCOUTCOMES.112.968172. Epub 2013 Mar 5.
To determine whether a pharmacist-led, Heart360-enabled, home blood pressure monitoring (HBPM) intervention improves blood pressure (BP) control compared with usual care (UC).
This randomized, controlled trial was conducted in 10 Kaiser Permanente Colorado clinics. Overall, 348 patients with BP above recommended levels were randomized to the HBPM (n=175) or UC (n=173) groups. There were no statistically significant differences in baseline characteristics between the groups; however, there was a trend toward a higher baseline BP for the HBPM group compared with the UC group (148.8 versus 145.5 mm Hg for systolic BP; 89.6 versus 88.0 mm Hg for diastolic BP). At 6 months, the proportion of patients achieving BP goal was significantly higher in the HBPM group (54.1%) than in the UC group (35.4%; P<0.001). Compared with the UC group, the HBPM group experienced a -12.4-mm Hg larger (95% confidence interval, -16.3 to -8.6) reduction in systolic BP and a -5.7-mm Hg larger (95% confidence interval, -7.8 to -3.6) reduction in diastolic BP. The impact of the intervention on BP reduction was even larger for the subgroup of patients with diabetes mellitus or chronic kidney disease. The HBPM group had more e-mail and telephone contacts and greater medication regimen intensification. The proportion of patients reporting high satisfaction with hypertension care was significantly greater in the HBPM group (58%) than in the UC group (42%), P<0.001.
A pharmacist-led, Heart360-supported, home BP monitoring intervention led to greater BP reductions, superior BP control, and higher patient satisfaction than UC.
确定由药剂师主导、采用Heart360技术支持的家庭血压监测(HBPM)干预措施与常规护理(UC)相比,是否能改善血压(BP)控制情况。
这项随机对照试验在科罗拉多州凯撒医疗机构的10家诊所进行。总体而言,348例血压高于推荐水平的患者被随机分为HBPM组(n = 175)和UC组(n = 173)。两组间基线特征无统计学显著差异;然而,与UC组相比,HBPM组的基线血压有升高趋势(收缩压分别为148.8和145.5 mmHg;舒张压分别为89.6和88.0 mmHg)。6个月时,HBPM组达到血压目标的患者比例(54.1%)显著高于UC组(35.4%;P<0.001)。与UC组相比,HBPM组收缩压降低幅度更大,为-12.4 mmHg(95%置信区间,-16.3至-8.6),舒张压降低幅度更大,为-5.7 mmHg(95%置信区间,-7.8至-3.6)。对于糖尿病或慢性肾病亚组患者,干预措施对血压降低的影响更大。HBPM组有更多的电子邮件和电话联系,且药物治疗方案强化程度更高。报告对高血压护理高度满意的患者比例,HBPM组(58%)显著高于UC组(42%),P<0.001。
与常规护理相比,由药剂师主导、Heart360技术支持的家庭血压监测干预措施能使血压降低幅度更大、血压控制更好且患者满意度更高。