Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, PR China.
J Colloid Interface Sci. 2013 May 1;397:39-44. doi: 10.1016/j.jcis.2013.01.063. Epub 2013 Feb 8.
Water dispersible carbon-dots (CDs) with tunable photoluminescence were synthesized via one-pot hydrothermal oxidation of nanodiamond and subsequently utilized for cell imaging applications. The CDs were characterized by the following techniques including transmission electron microscopy, atomic force microscopy, Fourier transform infrared spectroscopy, UV-Visible spectroscopy, and fluorescent spectroscopy. Results showed that the size of CDs is mainly distributed at 3-7 nm. Many functional groups were introduced on the surface of CDs during hydrothermal oxidation procedure. Cell morphology observation and cell viability measurement demonstrated the good biocompatibility of CDs, suggesting their potential bioimaging applications.
水相分散的碳点（CDs）具有可调谐的光致发光性能，通过纳米金刚石的一锅水热氧化法合成，并随后用于细胞成像应用。通过透射电子显微镜、原子力显微镜、傅里叶变换红外光谱、紫外-可见光谱和荧光光谱对 CDs 进行了表征。结果表明，CDs 的尺寸主要分布在 3-7nm 之间。在水热氧化过程中，CDs 表面引入了许多功能基团。细胞形态观察和细胞活力测量表明 CDs 具有良好的生物相容性，这表明它们具有潜在的生物成像应用。
