扁形虫涡虫作为本科研究经历中的毒理学和行为药理学动物模型。

Pagán Oné R, Coudron Tamara, Kaneria Tanvi

Department of Biology, West Chester University, 750 S. Church St., West Chester, PA 19383-2112.

J Undergrad Neurosci Educ. 2009 Spring;7(2):A48-52. Epub 2009 Jun 15.

In this work we describe a series of simple protocols using planaria as an animal model in toxicology and behavioral pharmacology. These procedures have proven useful to provide significant research experience to undergraduate students, including coauthorship in peer-reviewed publications. The methods described in this work have proven useful to allow students to visualize concepts related to concentration-effect curves for toxicity and behavioral experiments, without the need to consider factors that must be taken into account when working with vertebrate animals.

在这项工作中，我们描述了一系列使用涡虫作为毒理学和行为药理学动物模型的简单实验方案。这些程序已被证明有助于为本科生提供重要的研究经验，包括在同行评审出版物上共同署名。这项工作中描述的方法已被证明有助于让学生直观理解与毒性和行为实验的浓度-效应曲线相关的概念，而无需考虑在使用脊椎动物时必须考虑的因素。