• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[长期摄入氧化氚对CBA小鼠正常杀伤功能的影响]

[Normal killer function in CBA mice as affected by long-term intake of tritium oxide].

作者信息

Kirillova E N

出版信息

Radiobiologiia. 1985 Nov-Dec;25(6):792-5.

PMID:4080996
Abstract

A study was made of the cytotoxic function of normal killers of CBA mice during long-term administration of tritium oxide in potable water (a cumulative absorbed dose of 8.7 Gy, dose-rate, 4.5 Gy/day) and at different times after termination of the radionuclide injection. A mean decrease of 20-30% in the lytic effect of the effectors from spleen of the experimental mice on cell-targets of K-562 human erythroleukosis was demonstrated by a 17-19-hour test with 51Cr. At later times after termination of action of tritium oxide, the cytotoxic effect of normal killers increased by 1.8 times as compared to intact controls of the same age.

摘要

对CBA小鼠正常杀伤细胞在长期饮用含氧化氚的水(累积吸收剂量为8.7 Gy,剂量率为4.5 Gy/天)期间以及放射性核素注射终止后的不同时间的细胞毒性功能进行了研究。通过用51Cr进行17 - 19小时的试验表明,实验小鼠脾脏效应细胞对K - 562人红白血病细胞靶标的裂解作用平均降低了20 - 30%。在氧化氚作用终止后的后期,正常杀伤细胞的细胞毒性作用比同年龄的完整对照增加了1.8倍。

相似文献

1
[Normal killer function in CBA mice as affected by long-term intake of tritium oxide].[长期摄入氧化氚对CBA小鼠正常杀伤功能的影响]
Radiobiologiia. 1985 Nov-Dec;25(6):792-5.
2
[The immunity indices of rats after the long-term action of tritium oxide or gamma irradiation].[氧化氚或γ射线长期作用后大鼠的免疫指标]
Radiobiologiia. 1990 Mar-Apr;30(2):175-8.
3
[The significance of immunity disorders in the development of tumorous effects during the long-term action of tritium in mice].[氚对小鼠长期作用过程中免疫紊乱在肿瘤效应发生发展中的意义]
Radiobiologiia. 1990 Mar-Apr;30(2):179-84.
4
[Dynamics of the activity of the normal mouse spleen killers after partial splenectomy].[部分脾切除术后正常小鼠脾脏杀伤细胞活性的动态变化]
Biull Eksp Biol Med. 1984 Sep;98(9):331-3.
5
[The recovery of humoral immunity after the long-term action of tritium oxide at different irradiation levels].[不同照射剂量的氧化氚长期作用后体液免疫的恢复情况]
Radiobiologiia. 1991 Jan-Feb;31(1):82-6.
6
[Inactivation of non-syngeneic hematopoietic stem cells by mouse lymphocytes after long-term exposure to tritium oxide].[长期暴露于氧化氚后小鼠淋巴细胞对非同源造血干细胞的失活作用]
Radiobiologiia. 1985 Mar-Apr;25(2):255-8.
7
[Heterogeneity of the effectors of natural killer activity in CBA mice].[CBA 小鼠自然杀伤活性效应物的异质性]
Tsitologiia. 1986 Sep;28(9):981-5.
8
Studies on the mechanism of natural killer cytotoxicity. III. Activation of NK cells by interferon augments the lytic activity of released natural killer cytotoxic factors (NKCF).自然杀伤细胞细胞毒性机制的研究。III. 干扰素对自然杀伤细胞的激活增强了释放的自然杀伤细胞细胞毒性因子(NKCF)的裂解活性。
J Immunol. 1983 Jun;130(6):2960-4.
9
[Effect of diucifon on the natural cytotoxic activity of splenic cells in old rats].[双醋酚汀对老年大鼠脾细胞自然细胞毒性活性的影响]
Biull Eksp Biol Med. 1988 Aug;106(8):189-91.
10
[Interleukin-2 restoration of the activity of natural killers during stress].[应激期间白细胞介素-2恢复自然杀伤细胞的活性]
Biull Eksp Biol Med. 1986 Mar;101(3):341-3.