Unit of Nanotechnology and Bioactive Natural Products, Post Graduate and Research Department of Zoology, C. Abdul Hakeem College, Melvisharam-632 509, Vellore District, Tamil Nadu, India.
J Environ Sci (China). 2012;24(6):1091-8. doi: 10.1016/s1001-0742(11)60845-0.
To evaluate the potential environmental effects of engineered nano metals, it is important to determine the adverse effects of various nanomaterials on aquatic species. Adult tilapia (Oreochromis mossambicus) were maintained in 10 L glass aquaria, and exposed to a graded series of synthesized silver nanoparticles (AgNPs) at 25, 50 and 75 mg/L for eight days. The LC50 value was 12.6 mg/L. Reduced activities of antioxidant enzymes and the contents of antioxidants were lowered in the gills and liver of fishes treated with AgNPs, which resulted in heavy accumulation of free radicals. Histopathological results imply that the balance between the oxidative and antioxidant system in the fish was broken down during Ag-NPs exposure. The principal concern related with the release of nanomaterials and their smaller particle may change the materials transport and potential toxicity to aquatic organisms compared to larger particles.
为了评估工程纳米金属的潜在环境影响，确定各种纳米材料对水生生物的不良影响非常重要。成年罗非鱼（Oreochromis mossambicus）在 10 升玻璃水族箱中饲养，并在 25、50 和 75mg/L 的浓度范围内暴露于一系列合成银纳米颗粒（AgNPs）中 8 天。LC50 值为 12.6mg/L。用 AgNPs 处理的鱼类的鳃和肝脏中的抗氧化酶活性降低，抗氧化剂含量降低，导致自由基大量积累。组织病理学结果表明，在 Ag-NPs 暴露期间，鱼类体内氧化和抗氧化系统之间的平衡被打破。与较大颗粒相比，与纳米材料及其较小颗粒的释放相关的主要问题可能会改变物质的运输和对水生生物的潜在毒性。
